Tendons are designed to withstand considerable loads but repetitive use often results in injuries, such as tendinopathy. Concurrent with overt symptoms, a number of histological and molecular changes occur within the collagen fibril constituents of tendon. Progress in understanding how collagen, and various other components of the human tendon, respond to acute and chronic loading is outlined in this Review.
- S. Peter Magnusson
- Henning Langberg
- Michael Kjaer
