Mice that lack the fission mitochondrial GTPase Drp1, are shown to die during embryonic development. Although Drp1 is not required for apoptosis, the absence of Drp1 leads to neuronal and synaptic defects due to a failure of elongated mitochondria to reach distal parts of axons.
- Naotada Ishihara
- Masatoshi Nomura
- Katsuyoshi Mihara
