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Pan-Arctic ice-wedge degradation in warming permafrost and its influence on tundra hydrology

The polygonal patterns in permafrost regions are caused by the formation of ice wedges. Observations of polygon evolution reveal that rapid ice-wedge melting has occurred across the Arctic since 1950, altering tundra hydrology.

Anna K. Liljedahl
Julia Boike
Donatella Zona
Research14 Mar 2016
Nature Geoscience

Volume: 9, P: 312-318
Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors

Structural and biophysical studies of the inhibition of bacterial serine hydroxymethyltransferase (SHMT) by a human SHMT inhibitor used for cancer therapy, (+)-SHIN-1, identify SHMT as a potent antibacterial target.

Yuko Makino
Chihiro Oe
Eiichi N. Kodama
ResearchOpen Access23 Jun 2022
Communications Biology

Volume: 5, P: 1-12

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Pan-Arctic ice-wedge degradation in warming permafrost and its influence on tundra hydrology

Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors

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