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Showing 51–100 of 190 results

Advanced filters: Author: Hiroshi Fukui Clear advanced filters

Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
PIP₃-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover

Min-Jue Xie
Yasuyuki Ishikawa
Makoto Sato
ResearchOpen Access13 Mar 2019
Scientific Reports

Volume: 9, P: 1-15
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Transgenic overexpression of Reg protein caused gastric cell proliferation and differentiation along parietal cell and chief cell lineages

Youichi Miyaoka
Yasunori Kadowaki
Yoshikazu Kinoshita
Research29 Apr 2004
Oncogene

Volume: 23, P: 3572-3579
Origin of the chiral charge density wave in transition-metal dichalcogenide

The mechanism of chiral symmetry breaking in condensed matter systems is not well understood. Now charge-lattice symmetry frustration has been shown to be a key factor governing chirality in a charge density wave of 1T-TiSe₂.

Kwangrae Kim
Hyun-Woo J. Kim
B. J. Kim
Research14 Oct 2024
Nature Physics

Volume: 20, P: 1919-1926
Integration of polygenic risk score with measured blood pressure reveals hidden risks of cardiovascular disease mortality: A Japanese prospective cohort study

Hiroshi Okumiyama
Ryosuke Fujii
Chihaya Koriyama
Research24 Dec 2025
Hypertension Research

Volume: 49, P: 585-595
A novel risk classification score for malignant ureteral obstruction: a multicenter prospective validation study

Kouji Izumi
Takashi Shima
Atsushi Mizokami
ResearchOpen Access24 Feb 2021
Scientific Reports

Volume: 11, P: 1-9
Isolation of a new protein factor required for activation of Raf-1 by Ha-Ras: partial purification from rat brain cytosols

Shin Mizutani
Hiroshi Koide
Yoshito Kaziro
Research04 Jun 1998
Oncogene

Volume: 16, P: 2781-2786
Preparation of Polysilane/Gold Bilayer Using Polysilane/2-(Methylthio)ethyl Methacrylate Block Copolymer

Yukihito Matsuura
Hiroshi Inoue
Kimihiro Matsukawa
Research15 Jul 2004
Polymer Journal

Volume: 36, P: 560-562
Experimental gene therapy against subcutaneously implanted glioma with a herpes simplex virus-defective vector expressing interferon-γ

Hiroshi Kanno
Satoshi Hattori
Micheal G Kaplitt
Research22 Oct 1999
Cancer Gene Therapy

Volume: 6, P: 147-155
Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3

Therapies are needed for the prevention of chondrocyte hypertrophy and thinning of articular cartilage, features of osteoarthritic joint destruction. Here, the authors show that interfering with Sik3 signalling can increase the size of the chondrocyte population and reduce severity of a surgically induced mouse model of osteoarthritis.

Yasuhito Yahara
Hiroshi Takemori
Noriyuki Tsumaki
ResearchOpen Access24 Mar 2016
Nature Communications

Volume: 7, P: 1-14
Competing charge-density wave instabilities in the kagome metal ScV₆Sn₆

A charge-density wave state was recently reported in the bilayer kagome metal ScV₆Sn₆, but its nature is debated. Here, using inelastic X-ray scattering, the authors observe two competing charge-density waves and find the ground state is promoted by a momentum-dependent electron-phonon interaction.

Saizheng Cao
Chenchao Xu
Yu Song
ResearchOpen Access23 Nov 2023
Nature Communications

Volume: 14, P: 1-10
Correction: Second home blood pressure measurements per occasion predict incident cardiovascular events in type 2 diabetes: KAMOGAWA-HBP study

Madoka Sumi
Emi Ushigome
Michiaki Fukui
Amendments and Corrections19 Nov 2025
Hypertension Research

Volume: 49, P: 1085
An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing

Toll-like receptor 9 detects microbial DNA, and is activated by cleavage in the endolysosome. Onji et al. discover that following cleavage, the two parts of the protein remain associated, and this interaction is required for DNA sensing.

Masahiro Onji
Atsuo Kanno
Kensuke Miyake
Research11 Jun 2013
Nature Communications

Volume: 4, P: 1-10
Postoperative residual neuropathic pain prevents return to work after cervical OPLL surgery: nationwide multicenter study

Kanji Mori
Masayuki Miyagi
Masashi Yamazaki
ResearchOpen Access28 Nov 2025
Scientific Reports

Volume: 15, P: 1-8
Sound velocity of hexagonal close-packed iron to the Earth’s inner core pressure

New constraints on the composition of Earth’s inner core are provided by experimental verification of Birch’s law for hexagonal close-packed iron to pressure above 300 gigapascals, about double the pressure achieved in previous investigations

Daijo Ikuta
Eiji Ohtani
Alfred Q. R. Baron
ResearchOpen Access25 Nov 2022
Nature Communications

Volume: 13, P: 1-8
Activity-dependent organization of prefrontal hub-networks for associative learning and signal transformation

Neuronal populations in the prefrontal cortex are involved in associative learning. Here the authors use longitudinal imaging and computational approaches in the mouse prefrontal cortex to observe changes in neuronal ensembles during fear conditioning.

Masakazu Agetsuma
Issei Sato
Takeharu Nagai
ResearchOpen Access06 Oct 2023
Nature Communications

Volume: 14, P: 1-22
Decrease in volume and density of foraminiferal shells with progressing ocean acidification

Azumi Kuroyanagi
Takahiro Irie
Kazuhiko Fujita
ResearchOpen Access07 Oct 2021
Scientific Reports

Volume: 11, P: 1-7
Delayed neutralizing antibody response in the acute phase correlates with severe progression of COVID-19

Hitoshi Kawasuji
Yoshitomo Morinaga
Yoshihiro Yamamoto
ResearchOpen Access16 Aug 2021
Scientific Reports

Volume: 11, P: 1-5
Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament

Masao Koda
Toshitaka Yoshii
Masashi Yamazaki
ResearchOpen Access07 Jun 2021
Scientific Reports

Volume: 11, P: 1-9
Decreased peripheral perfusion measured by perfusion index is a novel indicator for cardiovascular death in patients with type 2 diabetes and established cardiovascular disease

Hiroshi Okada
Muhei Tanaka
Michiaki Fukui
ResearchOpen Access22 Jan 2021
Scientific Reports

Volume: 11, P: 1-7
Brain/MINDS Marmoset Brain Atlas 2.0: Population Cortical Parcellation With Multi-Modal Templates

Rui Gong
Noritaka Ichinohe
Alexander Woodward
ResearchOpen Access16 Jan 2026
Scientific Data

Volume: 13, P: 1-24
Quantitative evaluation of digital-image enhancement during heads-up surgery

Kunihiko Akiyama
Ken Watanabe
Toru Noda
ResearchOpen Access04 Nov 2019
Scientific Reports

Volume: 9, P: 1-7
Peripheral perfusion, measured by perfusion index, is a novel indicator for renal events in patients with type 2 diabetes mellitus

Hiroshi Okada
Muhei Tanaka
Michiaki Fukui
ResearchOpen Access08 Apr 2020
Scientific Reports

Volume: 10, P: 1-7
First-principles calculations of the epsilon phase of solid oxygen

Le The Anh
Masahiro Wada
Toshiaki Iitaka
ResearchOpen Access19 Jun 2019
Scientific Reports

Volume: 9, P: 1-12
Author Correction: Association of ketamine use with lower risks of post-intubation hypotension in hemodynamically-unstable patients in the emergency department

Tadayoshi Ishimaru
Tadahiro Goto
Akihiko Inoue
Amendments and CorrectionsOpen Access05 Feb 2020
Scientific Reports

Volume: 10, P: 1-2
Effect of cation substitution on bridgmanite elasticity: A key to interpret seismic anomalies in the lower mantle

Hiroshi Fukui
Akira Yoneda
Alfred Q. R. Baron
ResearchOpen Access19 Sept 2016
Scientific Reports

Volume: 6, P: 1-10
Allylic Polymers III. Electronic Effects of Acyloxy Group in Allyl Alkanoates on Polymerization Parameters

Yasumasa Shigetomi
Naruhito Ono
Michinori Oki
Research01 Jan 1992
Polymer Journal

Volume: 24, P: 99-105
Synthesis of Alternating Copolymalonamides by Ring-Opening Polyaddition Reaction of Bismalonimide with Diamines

Yoshio Imai
Hiroshi Hirukawa
Research01 Jan 1973
Polymer Journal

Volume: 4, P: 93-99
How Does Deep Breathing Affect Office Blood Pressure and Pulse Rate?

Hisao Mori
Hareaki Yamamoto
Satoshi Umemura
Research01 Jun 2005
Hypertension Research

Volume: 28, P: 499-504
Allylic Polymers V. Electronic Effects of Acyloxy Group in Allyl Chloroacetates on Homopolymerization

Naruhito Ono
Yasumasa Shigetomi
Michinori Oki
Research01 Sept 1992
Polymer Journal

Volume: 24, P: 951-957
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Identification of Macrolide Antibiotic-binding Human_p8 Protein

Tetsuro Morimura
Mio Hashiba
Fumio Sugawara
Research01 May 2008
The Journal of Antibiotics

Volume: 61, P: 291-296
Oriented Crystallization of Polycarbonate by Vapor Grown Carbon Fiber and its Application

Tatsuhiro Takahashi
Ayumu Higuchi
Tokio Kikuchi
Research13 Dec 2005
Polymer Journal

Volume: 37, P: 887-893
Control of π-Radical Anion State of Porphyrin with a Polymer Matrix

Hiroshi Segawa
Takeo Shimidzu
Ken-ichi Honda
Research01 Jun 1988
Polymer Journal

Volume: 20, P: 441-446
Tuning methane decomposition on stepped Ni surface: The role of subsurface atoms in catalyst design

Ryan Lacdao Arevalo
Susan Meñez Aspera
Hideaki Kasai
ResearchOpen Access25 Oct 2017
Scientific Reports

Volume: 7, P: 1-8
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

The characteristics of the cell type(s) responsible for initiating protective gut immune responses are not fully defined. Akira and colleagues show that TLR5⁺ lamina propria dendritic cells trigger, in a retinoic-dependent way, the production of interleukin 17 and immunoglobulin A.

Satoshi Uematsu
Kosuke Fujimoto
Shizuo Akira
Research30 May 2008
Nature Immunology

Volume: 9, P: 769-776
Current Status of Sids Prevention Activity in Japan

Hiroshi Nishida
Toshiko Sawaguchi
Stephanie Fukui
Research01 May 1999
Pediatric Research

Volume: 45, P: 11
Direct plasma treatment of caryopses after flowering in brewer’s rice cultivar Yamadanishiki enhanced those grain qualities through “Smart Agriculture System”

Hiroshi Hashizume
Hidemi Kitano
Masaru Hori
ResearchOpen Access27 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
Control of cell polarity and motility by the PtdIns(3,4,5)P₃ phosphatase SHIP1

Miki Nishio
Ken-ichi Watanabe
Takehiko Sasaki
Research17 Dec 2006
Nature Cell Biology

Volume: 9, P: 36-44
Interaction between Amlodipine and Simvastatin in Patients with Hypercholesterolemia and Hypertension

Shinichiro Nishio
Hiroshi Watanabe
Kyoichi Ohashi
Research01 Mar 2005
Hypertension Research

Volume: 28, P: 223-227
Local Chain Dynamics of Poly(N-vinylcarbazole) Studied by the Fluorescence Depolarization Method

Hiroyuki Aoki
Jun-ichi Horinaka
Mitsuo Sawamoto
Research01 Jun 2001
Polymer Journal

Volume: 33, P: 464-468
Current Status of Antihypertensive Prescription and Associated Blood Pressure Control in Japan

Hisao Mori
Hiroshi Ukai
Satoshi Umemura
Research01 Mar 2006
Hypertension Research

Volume: 29, P: 143-151
Inhibition of Vascular Angiotensin-Converting Enzyme by Telmisartan via the Peroxisome Proliferator–Activated Receptor γ Agonistic Property in Rats

Shinji Takai
Denan Jin
Mizuo Miyazaki
Research01 Dec 2007
Hypertension Research

Volume: 30, P: 1231-1237
Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death

Many forms of autoimmune disorder involve abnormal T cell functions, but how this versatility is achieved is not fully clear. Here the authors show that Sharpin-deficient Treg cells induce the death of local keratinocytes via multiple programmed cell death and innate inflammation to cause skin inflammation similar to cpdm mice with genetic deletion of Sharpin.

Katsuhiro Sasaki
Ai Himeno
Kazuhiro Iwai
ResearchOpen Access28 Aug 2019
Nature Communications

Volume: 10, P: 1-16
Perinatal outcomes in RhD-negative pregnant women in Japan

Ken Takahashi
Susumu Yoshida
Osamu Samura
ResearchOpen Access22 Mar 2025
Scientific Reports

Volume: 15, P: 1-10
The prevalence and clinical features of MYO7A-related hearing loss including DFNA11, DFNB2 and USH1B

Kizuki Watanabe
Shin-ya Nishio
Shunsuke Kondo
ResearchOpen Access09 Apr 2024
Scientific Reports

Volume: 14, P: 1-19
Seasonal variation in home blood pressure during pregnancy and frequency of hypertensive disorders of pregnancy: a multicenter prospective study of home blood pressure measurements in pregnant women using information technology

Seung Chik Jwa
Natsuko Takano
Hiroyuki Seki
Research23 Oct 2024
Hypertension Research

Volume: 48, P: 110-120
Time–outcome relationship in acute large-vessel occlusion exists across all ages: subanalysis of RESCUE-Japan Registry 2

Kenichi Todo
Shinichi Yoshimura
Naoyuki Uchiyama
ResearchOpen Access17 Jun 2021
Scientific Reports

Volume: 11, P: 1-10
Author Correction: New theropod dinosaur from the Lower Cretaceous of Japan provides critical implications for the early evolution of ornithomimosaurs

Soki Hattori
Masateru Shibata
Yoichi Azuma
Amendments and CorrectionsOpen Access28 Sept 2023
Scientific Reports

Volume: 13, P: 1

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