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Showing 1–8 of 8 results
Advanced filters: Author: Hirotaka Ejima Clear advanced filters
  • Individuals with autism often exhibit social memory impairment. Here, authors show the disruption of autism-associate Shank3 gene in more than a certain proportion of hippocampal ventral CA1 neurons impairs social memory, through AAV- and extracellular vesicle-mediated in vivo gene editing.

    • Myung Chung
    • Katsutoshi Imanaka
    • Teruhiro Okuyama
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11
  • Realizing robust underwater adhesion is challenging because a hydration layer impedes the interaction between substrates and adhesives. Here, the authors report a class of ultrastrong underwater adhesives with molecular non-canonical phenolic groups in a polymer to realize strong adhesion on various substrates.

    • Bohan Cheng
    • Jinhong Yu
    • Hirotaka Ejima
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9
  • This focus review summarizes advances in the recently emerging field of phenolic film engineering for template-mediated microcapsule preparation. By depositing polyphenol films on sacrificial particulate templates and subsequently removing the templates, hollow microcapsules can be readily prepared. Due to the pH-responsive properties, negligible cytotoxicity and the bioactivities of the phenolic building blocks (dopamine and tannic acid), phenolic microcapsules are promising for biomedical applications.

    • Hirotaka Ejima
    • Joseph J Richardson
    • Frank Caruso
    Reviews
    Polymer Journal
    Volume: 46, P: 452-459
  • Periodic lamellar nanostructures have been created in polymer blend thin films composed of poly(L-lactide) (PLLA) and poly(vinyl phenol) (PVPh) via directional solidification and epitaxial crystallization. The obtained morphology was strongly dependent on annealing condition and blending ratio. These processing parameters closely correlate to the strength of the hydrogen bonding between PLLA and PVPh, hence it was highlighted that the noncovalent interaction between polymers affects the pattern formation.

    • Xin Zhang
    • Hirotaka Ejima
    • Naoko Yoshie
    Research
    Polymer Journal
    Volume: 47, P: 498-504
  • Here, biological attributes of two early human isolates of the newly emerged H7N9 influenza viruses are characterized: the potential of these viruses to infect and/or transmit within various animal models is discussed, as is their relative sensitivity to neuraminidase inhibitors and experimental polymerase inhibitors compared to an H1N1 pandemic strain.

    • Tokiko Watanabe
    • Maki Kiso
    • Yoshihiro Kawaoka
    Research
    Nature
    Volume: 501, P: 551-555