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Classification accuracy of pain intensity induced by leg blood flow restriction during walking using machine learning based on electroencephalography

Hirotatsu Imai
Yuya Kanie
Seiji Okada
ResearchOpen Access31 Jul 2025
Scientific Reports

Volume: 15, P: 1-10
Delivery of a BET protein degrader via a CEACAM6-targeted antibody–drug conjugate inhibits tumour growth in pancreatic cancer models

Therapeutic options for pancreatic ductal adenocarcinoma (PDAC) are limited. Here the authors report the characterization of a CEACAM6-targeting antibody drug conjugate loaded with a BET protein degrader, showing antitumour activity in PDAC preclinical models.

Youya Nakazawa
Masayuki Miyano
Akihito Machinaga
ResearchOpen Access11 Mar 2024
Nature Communications

Volume: 15, P: 1-17
Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations

Kei Maruyama
Hirotatsu Imai
Toshio Uchiumi
ResearchOpen Access14 Oct 2019
Scientific Reports

Volume: 9, P: 1-9

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