Tetrasubstituted alkenes are found in bioactive compounds and materials, but modular stereospecific synthesis of these compounds remains challenging due to reactivity and selectivity issues of the intermediate compounds. Here, the authors disclose a carboboration of alkynyl selenides, which provides an intermediate with two readily distinguishable sites of functionalization, providing rapid access to stereodefined tetrasubstituted alkenes.
- Xuan Di
- Sitian Zhou
- Hongming Jin
