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Showing 1–2 of 2 results
Advanced filters: Author: Hope E. Merens Clear advanced filters

  • Kramer, Prakash et al. share genome-wide CRISPR screens for factors that alter the levels of two dual-genome-encoded Complex IV subunits, COX1 and COX4. They identify PREPL and NME6 as genes that connect mitochondrial metabolism to mtDNA expression.

    • Nicholas J. Kramer
    • Gyan Prakash
    • L. Stirling Churchman
    Research
    Nature Cell Biology
    Volume: 25, P: 1575-1589

  • In this extension to their NET-seq protocol, the authors combine isolation of 4sU-labeled chromatin-associated nascent RNA with long-read direct RNA sequencing on nanopores to profile the kinetics and patterns of co-transcriptional RNA processing.

    • Heather L. Drexler
    • Karine Choquet
    • L. Stirling Churchman
    Protocols
    Nature Protocols
    Volume: 16, P: 1343-1375