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Showing 1–2 of 2 results
Advanced filters: Author: Hossein Batebi Clear advanced filters

  • Using molecular dynamics simulations and functional assays, authors track the structural changes in heterotrimeric G proteins in response to receptor coupling that lead to the ejection of GDP, the rate-limiting step during G-protein activation.

    • Hossein Batebi
    • Guillermo Pérez-Hernández
    • Peter W. Hildebrand
    Research
    Nature Structural & Molecular Biology
    Volume: 31, P: 1692-1701

  • Time-resolved cryo-EM is used to capture structural transitions during G-protein activation stimulated by a G-protein-coupled receptor.

    • Makaía M. Papasergi-Scott
    • Guillermo Pérez-Hernández
    • Georgios Skiniotis
    Research
    Nature
    Volume: 629, P: 1182-1191