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Showing 1–5 of 5 results

Advanced filters: Author: Hsiao-Lin Lee Clear advanced filters

A common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators

A common East Asian-specific defect of an alcohol metabolizing enzyme (ALDH2) causes glucose abnormality, obesity, and fatty liver. Here, the authors show an ALDH2 activator can treat these metabolic disorders in mice.

Yi-Cheng Chang
Hsiao-Lin Lee
Lee-Ming Chuang
ResearchOpen Access25 Sept 2023
Nature Communications

Volume: 14, P: 1-16
Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma

Sojka et al. analyse the transcriptomic and epigenomic landscape of human astrocyte maturation and identify an epigenetically regulated intermediate state associated with aberrant development in glioblastoma.

Caitlin Sojka
Hsiao-Lin V. Wang
Steven A. Sloan
Research08 Jan 2025
Nature Cell Biology

Volume: 27, P: 347-359
Y-SNP Haplogroup Hierarchy Finder: a web tool for Y-SNP haplogroup assignment

Bill Tseng
Hsiao-Lin Hwa
James Chun-I Lee
Research28 Mar 2022
Journal of Human Genetics

Volume: 67, P: 487-493
A genome-wide association study for melatonin secretion

Pi-Hua Liu
Gwo-Tsann Chuang
Yi-Cheng Chang
ResearchOpen Access16 May 2022
Scientific Reports

Volume: 12, P: 1-8
Genome-wide association study for circulating fibroblast growth factor 21 and 23

Gwo-Tsann Chuang
Pi-Hua Liu
Yi-Cheng Chang
ResearchOpen Access03 Sept 2020
Scientific Reports

Volume: 10, P: 1-12