Chung et al. introduce Pre-Pro as a loss-less pre-processor incorporating a fast dimension-reduction (2SDR) de-noiser to enhance 2D classification. Implementing it in representative classification algorithm like RELION and ISAC, they further demonstrate faster classification, improved quality of class-average images and yield of good particles which improve the final resolution.
- Szu-Chi Chung
- Hsin-Hung Lin
- Wei-Hau Chang