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Showing 1–6 of 6 results

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Protective efficacy of Ad26.COV2.S against SARS-CoV-2 B.1.351 in macaques

SARS-CoV-2 challenge of rhesus macaques demonstrates that the Ad26.COV2.S vaccine induces robust protection against both the WA1/2020 isolate and the B.1.351 variant of concern.

Jingyou Yu
Lisa H. Tostanoski
Dan H. Barouch
ResearchOpen Access23 Jun 2021
Nature

Volume: 596, P: 423-427
Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

The protective efficacy of a single dose of adenovirus serotype 26 (Ad26) vector-based vaccine expressing the SARS-CoV-2 spike protein in non-human primates is demonstrated.

Noe B. Mercado
Roland Zahn
Dan H. Barouch
Research30 Jul 2020
Nature

Volume: 586, P: 583-588
Long-acting capsid inhibitor protects macaques from repeat SHIV challenges

A single dose of a small-molecule HIV capsid inhibitor provides long-term protection from repeated simian–human immunodeficiency virus challenges in macaques and might serve as a novel strategy for HIV prevention in humans.

Samuel J. Vidal
Elena Bekerman
Dan H. Barouch
ResearchOpen Access07 Dec 2021
Nature

Volume: 601, P: 612-616
Publisher Correction: Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

Noe B. Mercado
Roland Zahn
Dan H. Barouch
Amendments and Corrections19 Jan 2021
Nature

Volume: 590, P: E25
mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant

A longitudinal study in mice reveals that a booster dose of mRNA vaccine BNT162b2 enhances humoral and cell-mediated responses and provides sterilizing immunity against Omicron-induced lung infection in aged animals.

Etsuro Nanishi
Marisa E. McGrath
David J. Dowling
ResearchOpen Access06 Aug 2022
Communications Biology

Volume: 5, P: 1-8
Durability and expansion of neutralizing antibody breadth following Ad26.COV2.S vaccination of mice

Shant H. Mahrokhian
Lisa H. Tostanoski
Dan H. Barouch
ResearchOpen Access23 Feb 2022
npj Vaccines

Volume: 7, P: 1-8