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Showing 1–3 of 3 results

Advanced filters: Author: Huangfan Xie Clear advanced filters

OTX2 inhibits human pluripotent stem cell reprogramming toward 8-cell-like and morula-like states

OTX2 acts as a barrier to the formation of human 8-cell-like and morula-like cells in vitro. Deleting OTX2 enhances their induction efficiency and developmental potential, uncovering key mechanisms of totipotency regulation and early human development.

Xi Kong
Nan Jiang
Bingqing Xie
ResearchOpen Access19 Jan 2026
Nature Communications

Volume: 17, P: 1-19
Targeting JNK pathway promotes human hematopoietic stem cell expansion

Xiong Xiao
Weifeng Lai
Hongkui Deng
ResearchOpen Access08 Jan 2019
Cell Discovery

Volume: 5, P: 1-12
A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts

Bingqing Xie
Da Sun
Hongkui Deng
ResearchOpen Access03 Jul 2019
Cell Research

Volume: 29, P: 696-710