Nature Search

Arginine-modified black phosphorus quantum dots with dual excited states for enhanced electrochemiluminescence in bioanalysis

Electrochemiluminescence is emitted via the radiative transition of a singlet or triplet excited state. Here, the authors propose an arginine modification of black phosphorus quantum dots that exhibits enhanced emission based on dual excited states.

Siqi Yu
Yu Du
Huangxian Ju
ResearchOpen Access26 Nov 2022
Nature Communications

Volume: 13, P: 1-9
Site-selected in situ polymerization for living cell surface engineering

Constructing polymer-based mimics on the surface of cells has potential to manipulate cell behavior, but precise control of grafting sites is challenging. Here, the authors report a method for site selected radical polymerization on cell surfaces by metabolic labelling.

Yihong Zhong
Lijia Xu
Huangxian Ju
ResearchOpen Access10 Nov 2023
Nature Communications

Volume: 14, P: 1-17
Intrareticular charge transfer regulated electrochemiluminescence of donor–acceptor covalent organic frameworks

Controlling the charge transfer between radical anions and cations is a promising way to tune the emission mechanism in electrochemiluminescence (ECL) systems. Here, the authors report a donor-acceptor based covalent organic framework, using triphenylamine and triazine building units, and demonstrate efficient ECL based on an adjustable intrareticular charge transfer.

Rengan Luo
Haifeng Lv
Jianping Lei
ResearchOpen Access23 Nov 2021
Nature Communications

Volume: 12, P: 1-9
Ratiometric electrochemical proximity assay for sensitive one-step protein detection

Kewei Ren
Jie Wu
Huangxian Ju
ResearchOpen Access12 Mar 2014
Scientific Reports

Volume: 4, P: 1-6
Bis-three-way junction nanostructure and DNA machineries for ultrasensitive and specific detection of BCR/ABL fusion gene by chemiluminescence imaging

Yongjie Xu
Xintong Bian
Shijia Ding
ResearchOpen Access31 Aug 2016
Scientific Reports

Volume: 6, P: 1-7
A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery

Delivery of siRNA to target cells is essential for in vivogene therapy. Here the authors demonstrate an oligonucleotide aptamer that targets therapeutic siRNA to a specific cell type.

Kewei Ren
Ying Liu
Huangxian Ju
ResearchOpen Access24 Nov 2016
Nature Communications

Volume: 7, P: 1-10
Device integration of electrochemical biosensors

Electrochemical biosensors can be integrated into wearable, portable and implantable devices for health monitoring and disease diagnosis. This Review discusses the design and integration of different types of electrochemical biosensors for the detection of analytes related to health and disease, and outlines engineering challenges that need to be addressed to enable clinical translation of electrochemical biosensor-based point-of-care devices.

Jie Wu
Hong Liu
Huangxian Ju
Reviews24 Feb 2023
Nature Reviews Bioengineering

Volume: 1, P: 346-360
Chemiluminescent screening of specific hybridoma cells via a proximity-rolling circle activated enzymatic switch

In order to realize fast screening of specific hybridoma cells in hybridoma technology, a 1-day chemiluminescent screening method is reported on common 96-well plate via a proximity-rolling circle activated enzymatic switch strategy.

Hang Ao
Weiwei Chen
Huangxian Ju
ResearchOpen Access04 Apr 2022
Communications Biology

Volume: 5, P: 1-9
Noninvasive imaging of sialyltransferase activity in living cells by chemoselective recognition

Lei Bao
Lin Ding
Huangxian Ju
ResearchOpen Access05 Jun 2015
Scientific Reports

Volume: 5, P: 1-11
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice

Sheng Zhou
Wanli Lu
Qing Jiang
ResearchOpen Access22 Feb 2017
Scientific Reports

Volume: 7, P: 1-14

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