Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Nature Cell Biology (2)
Nature Chemical Biology (1)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (3)

Subject Check one or more subjects to show results from those subjects only.

Biophysics
Cell biology
Chemical biology
Molecular biology

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–3 of 3 results

Advanced filters: Author: Huanyi Fu Clear advanced filters

Stabilization of AFF1 by PARylation ensures transcriptional restart after DNA damage

Zhu, Fu, Zhu, Li and colleagues found that the key DNA repair enzyme poly(ADP-ribose) polymerase 1 promotes transcriptional restart after DNA damage through PARylating and stabilizing AFF1 by preventing its ubiquitylation by the E3 ligase Siah1.

Feifeng Zhu
Huanyi Fu
Huasong Lu
Research08 Oct 2025
Nature Chemical Biology

P: 1-14
Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage

Fu, et al. report that PARP1-dependent poly(ADP-ribsoyl)ation of the P-TEFb subunit CycT1 suppresses its phase separation, which prevents its interaction partner CDK9 from hyperphosphorylating RNA polymerase II and thereby blocks transcription.

Huanyi Fu
Rongdiao Liu
Qiang Zhou
Research07 Apr 2022
Nature Cell Biology

Volume: 24, P: 513-525
A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation

Shao et al. report that FUS interacts with the transcriptional coactivator TAZ, maintaining liquid-like properties of TAZ biomolecular condensates and enhancing TAZ transcriptional activity.

Yangqing Shao
Xin Shu
Huasong Lu
Research03 Jan 2024
Nature Cell Biology

Volume: 26, P: 86-99