Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Hunter Nisonoff Clear advanced filters

  • Generating RNA sequences with improved function remains challenging. Here, authors present an RNA database for RNA structural and functional analysis. They use this database and the RNA generative models to identify RNA mutations that increase the thermostability of a bacterial ribosome.

    • Yekaterina Shulgina
    • Marena I. Trinidad
    • Jamie H. D. Cate
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • A massively parallel assay developed to map the essential photosynthetic enzyme rubisco showed that non-trivial biochemical changes and improvements in CO2 affinity are possible, signposting further enzyme engineering efforts to increase crop yields.

    • Noam Prywes
    • Naiya R. Phillips
    • David F. Savage
    ResearchOpen Access
    Nature
    Volume: 638, P: 823-828

  • Finding a biologically-relevant inductive bias for training DNNs on large fitness landscapes is challenging. Here, the authors propose a method called Epistatic Net that improves DNN prediction accuracy and interpretation speed by integrating the knowledge that higher-order epistatic interactions are usually sparse.

    • Amirali Aghazadeh
    • Hunter Nisonoff
    • Kannan Ramchandran
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10