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Showing 1–5 of 5 results

Advanced filters: Author: I. Cody MacDonald Clear advanced filters

Enhanced regulation of prokaryotic gene expression by a eukaryotic transcriptional activator

Expanded toolkits for prokaryotic synthetic biology can enhance the dynamic range of gene expression. Here the authors move the eukaryotic transcription factor QF into E. coli and integrate it into genetic devices.

I. Cody MacDonald
Travis R. Seamons
Tara L. Deans
ResearchOpen Access05 Jul 2021
Nature Communications

Volume: 12, P: 1-10
Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

Xuchu Que
Ming-Yow Hung
Joseph L. Witztum
Amendments and Corrections16 Jul 2018
Nature

Volume: 561, P: E43
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

A single-chain variable fragment of the antibody E06, which binds to the phosphocholine headgroup of oxidized phospholipids, blocks the uptake of oxidized low-density lipoprotein by macrophages, and reduces inflammation and atherosclerosis in hypercholesterolaemic mice.

Xuchu Que
Ming-Yow Hung
Joseph L. Witztum
Research06 Jun 2018
Nature

Volume: 558, P: 301-306
Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production

The first global metabolic models that incorporate reactive oxygen species in E. coli reveal targets for potentiating the action of antibacterials.

Mark P Brynildsen
Jonathan A Winkler
James J Collins
Research06 Jan 2013
Nature Biotechnology

Volume: 31, P: 160-165
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22