The most-established risk factors for intracerebral haemorrhage (ICH) are lifestyle-related, but several studies have reported familial aggregation of ICH. An understanding of the role of genetic risk factors in ICH could provide insight into ICH aetiopathogenesis, and improve prevention and patient-tailored management of ICH. This Review discusses the evidence for a genetic component in ICH, taking into account the strength of evidence and functional relevance to ICH for each genetic variant.
- Amanda M. Carpenter
- Inder P. Singh
- Charles J. Prestigiacomo
