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Showing 501–506 of 506 results
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  • Behavioural changes have a major impact on the quality of life of patients with neurodegenerative diseases. Cummings and Zhong discuss how new tools for studying behaviour and improved clinical trial methodologies are facilitating drug development for this large unmet medical need.

    • Jeffrey L. Cummings
    • Kate Zhong
    Reviews
    Nature Reviews Drug Discovery
    Volume: 5, P: 64-74

  • We reviewed our recent studies on optical manipulation techniques for microspectroscopic analysis of optically trapped polymers. A focused laser beam exerts an optical force on polymer chains, leading to the microassembly formation of them. We applied the conventional optical tweezers for the concentration determination techniques of phase-separated thermoresponsive polymer chains by combining with microspectroscopies. To overcome the limitations of the conventional optical tweezers, localized surface plasmon has attracted much attention. Finally, we introduced our original manipulation technique based on nanostructured semiconductor-assisted optical tweezers; NASSCA optical tweezers.

    • Tatsuya Shoji
    • Yasuyuki Tsuboi
    Reviews
    Polymer Journal
    Volume: 53, P: 271-281

  • Are reverse mergers the answer to biotech's capital crunch? This IPO alternative, in which a viable company goes public through a defunct 'shell' company that no longer has operations, is becoming increasingly popular. But it pays to understand the downside, too.

    • Elizabeth Silverman
    Comments & Opinion
    Bioentrepreneur
    P: 1-3

  • A blocking patent can kill your business before it's off the ground.

    • Y Philip Zhang
    Comments & Opinion
    Bioentrepreneur
    P: 1-3