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Showing 1–2 of 2 results
Advanced filters: Author: Iakov I. Davydov Clear advanced filters

  • The ribosomal stalk L12 is the only multi-copy protein in the ribosome and is essential for translation. Here Davydov et al.use a bioinformatics and mass spectrometry approach to study the evolution of L12 in bacterial ribosomes and predict its stoichiometry in a wide range of species.

    • Iakov I. Davydov
    • Ingo Wohlgemuth
    • Marina V. Rodnina
    Research
    Nature Communications
    Volume: 4, P: 1-10

  • Using 13 intermediate-translocation-state models derived from X-ray and cryo-EM structures of Escherichia coli ribosomes to guide large-scale molecular dynamics simulations, a new study now models the path taken by tRNAs during spontaneous translocation to uncover the mechanisms that facilitate tRNA movement through the ribosome.

    • Lars V Bock
    • Christian Blau
    • Helmut Grubmüller
    Research
    Nature Structural & Molecular Biology
    Volume: 20, P: 1390-1396