Nature Search

Author Correction: Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing

Dicky Pranantyo
Chun Kiat Yeo
Mary B. Chan-Park
Amendments and CorrectionsOpen Access10 Oct 2025
Nature Communications

Volume: 16, P: 1-5
The genomic landscape of 2,023 colorectal cancers

Whole-genome sequencing of more than 2,000 colorectal carcinoma samples provides a highly detailed view of the genomic landscape of this cancer and identifies new driver mutations.

Alex J. Cornish
Andreas J. Gruber
Richard S. Houlston
ResearchOpen Access07 Aug 2024
Nature

Volume: 633, P: 127-136
Sex differences in oncogenic mutational processes

There’s an emerging body of evidence to show how biological sex impacts cancer incidence, treatment and underlying biology. Here, using a large pan-cancer dataset, the authors further highlight how sex differences shape the cancer genome.

Constance H. Li
Stephenie D. Prokopec
Christian von Mering
ResearchOpen Access28 Aug 2020
Nature Communications

Volume: 11, P: 1-24
Myelination of the brain in Major Depressive Disorder: An in vivo quantitative magnetic resonance imaging study

Matthew D. Sacchet
Ian H. Gotlib
ResearchOpen Access19 May 2017
Scientific Reports

Volume: 7, P: 1-14
Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Clinical multi-omics data are integrated and analyzed using a generative deep-learning model.

Rosa Lundbye Allesøe
Agnete Troen Lundgaard
Moustafa Abdalla
ResearchOpen Access02 Jan 2023
Nature Biotechnology

Volume: 41, P: 399-408
Self-reports map the landscape of task states derived from brain imaging

Using machine learning, this study shows that self-reported experience of task states maps onto ‘brain space’, i.e., features of different task states identified in fMRI.

Brontë Mckeown
Ian Goodall-Halliwell
Jonathan Smallwood
ResearchOpen Access22 Jan 2025
Communications Psychology

Volume: 3, P: 1-16
A mega-analysis of functional connectivity and network abnormalities in youth depression

This mega-analysis of brain resting-state functional connectivity in young individuals with major depressive disorder scanned at six sites across four countries identified hub regions of the attentional and default mode networks as predictors of depression severity.

Nga Yan Tse
Aswin Ratheesh
Andrew Zalesky
Research23 Sept 2024
Nature Mental Health

Volume: 2, P: 1169-1182
Large-Scale Hypoconnectivity Between Resting-State Functional Networks in Unmedicated Adolescent Major Depressive Disorder

Matthew D Sacchet
Tiffany C Ho
Tony T Yang
Research26 May 2016
Neuropsychopharmacology

Volume: 41, P: 2951-2960
Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders

Stewart Sell
Ralph Buttyan
Ian Guest
ResearchOpen Access27 Jun 2011
Nature Precedings

P: 1
Plasma proteomics of acute tubular injury

Acute tubular injury (ATI) significantly contributes to many kidney diseases. Here, the authors identify several immune response and cellular stress plasma proteins linked to ATI severity and acute kidney injury, which may aid in non-invasive ATI assessment.

Insa M. Schmidt
Aditya L. Surapaneni
Sushrut S. Waikar
ResearchOpen Access27 Aug 2024
Nature Communications

Volume: 15, P: 1-11
Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries

An analysis of 52 million births in 26 countries shows small reductions in preterm birth during the first to third months of lockdown. Further research is needed to examine causal pathways.

Clara Calvert
Meredith (Merilee) Brockway
Meghan B. Azad
ResearchOpen Access27 Feb 2023
Nature Human Behaviour

Volume: 7, P: 529-544
Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma

MYC amplification is an independent prognostic factor for the most aggressive subgroup (Group 3) of pediatric medulloblastoma (G3 MB). Here, the authors highlight the role of the RNA-binding protein, Musashi-1 (MSI1) in G3 MB and identify MSI1-bound targets sharing MYC associated pathways.

Michelle M. Kameda-Smith
Helen Zhu
Sheila K. Singh
ResearchOpen Access06 Dec 2022
Nature Communications

Volume: 13, P: 1-19
Pneumatic displacement of submacular haemorrhage secondary to neovascular age-related macular degeneration and polypoidal choroidal vasculopathy

Shaun Sebastian Sim
Kai Xiong Cheong
Kelvin Yi Chong Teo
Research19 Sept 2024
Eye

Volume: 38, P: 3374-3381
Striatal dopamine deficits predict reductions in striatal functional connectivity in major depression: a concurrent ¹¹C-raclopride positron emission tomography and functional magnetic resonance imaging investigation

J. Paul Hamilton
Matthew D. Sacchet
Ian H. Gotlib
ResearchOpen Access30 Nov 2018
Translational Psychiatry

Volume: 8, P: 1-10
Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations

Analyses of neuroimaging datasets from 5,306 participants across 15 countries found generally larger brain-age gaps in Latin American compared with non-Latin American populations, which were influenced by disparities in socioeconomic and health-related factors.

Sebastian Moguilner
Sandra Baez
Agustin Ibanez
ResearchOpen Access26 Aug 2024
Nature Medicine

Volume: 30, P: 3646-3657
Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing

Dressings for aiding in chronic wound healing can be beneficial, but often involve additional processes or leave residue. Here, the authors report a hydrogel dressing with antibiofilm and antioxidative properties for the treatment of infected diabetic wounds.

Dicky Pranantyo
Chun Kiat Yeo
Mary B. Chan-Park
ResearchOpen Access01 Feb 2024
Nature Communications

Volume: 15, P: 1-19
Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission

Emerging SARS-CoV-2 variants of concern were detected early and multiple cases of virus spread not captured by clinical genomic surveillance were identified using high-resolution wastewater and clinical sequencing.

Smruthi Karthikeyan
Joshua I. Levy
Rob Knight
ResearchOpen Access07 Jul 2022
Nature

Volume: 609, P: 101-108
New loci and coding variants confer risk for age-related macular degeneration in East Asians

Age-related macular degeneration (AMD) is a major cause of blindness worldwide. Here, the authors carry out a two-stage genome-wide association study for AMD and identify three new AMD risk loci, highlighting the shared and distinct genetic basis of the disease in East Asians and Europeans.

Ching-Yu Cheng
Kenji Yamashiro
Chiea Chuen Khor
ResearchOpen Access28 Jan 2015
Nature Communications

Volume: 6, P: 1-10
Inflexible Functional Connectivity of the Dorsal Anterior Cingulate Cortex in Adolescent Major Depressive Disorder

Tiffany C Ho
Matthew D Sacchet
Tony T Yang
Research29 May 2017
Neuropsychopharmacology

Volume: 42, P: 2434-2445
Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma

Michelle M. Kameda-Smith
Helen Zhu
Sheila K. Singh
Amendments and CorrectionsOpen Access10 Jan 2023
Nature Communications

Volume: 14, P: 1
A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy

Zhenglin Yang and colleagues use whole-exome sequencing to identify a rare variant in the FGD6 gene that is associated with the polypoidal choroidal vasculopathy subtype of wet age-related macular degeneration. They show that FGD6 regulates proangiogenic effects together with VEGF and that the mutation results in abnormal retinal vessel development.

Lulin Huang
Houbin Zhang
Zhenglin Yang
Research18 Apr 2016
Nature Genetics

Volume: 48, P: 640-647
Brain-behaviour modes of covariation in healthy and clinically depressed young people

Agoston Mihalik
Fabio S. Ferreira
Janaina Mourão-Miranda
ResearchOpen Access08 Aug 2019
Scientific Reports

Volume: 9, P: 1-11
25-years Trends and Risk factors related to Surgical Outcomes of Giant Retinal Tear-Rhegmatogenous Retinal Detachments

Daniel S. W. Ting
Valencia H. X. Foo
Shu Yen Lee
ResearchOpen Access25 Mar 2020
Scientific Reports

Volume: 10, P: 1-8
Design, implementation, and evaluation of a nurse-led intravitreal injection programme for retinal diseases in Singapore

Alvin Wei Jun Teo
Tyler Hyungtaek Rim
Ian Yew San Yeo
Research07 May 2020
Eye

Volume: 34, P: 2123-2130
Detection of genotyping errors by Hardy–Weinberg equilibrium testing

Louise Hosking
Sheena Lumsden
Chun-Fang Xu
Research11 Feb 2004
European Journal of Human Genetics

Volume: 12, P: 395-399
Choroidal Remodeling in Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy: A 12-month Prospective Study

Daniel Shu Wei Ting
Yasuo Yanagi
Gemmy Chui Ming Cheung
ResearchOpen Access11 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

John Chambers, Jaspal Kooner, Pim van der Harst, Shyong Tai, Paul Elliott, Jiang He, Norihiro Kato and colleagues performed a genome-wide association study of blood pressure phenotypes in individuals of European, East Asian and South Asian ancestry. They find trait-associated SNPs at 12 loci, some of which are associated with methylation at nearby CpG sites.

Norihiro Kato
Marie Loh
John C Chambers
Research21 Sept 2015
Nature Genetics

Volume: 47, P: 1282-1293
Colorimetric histology using plasmonically active microscope slides

Colour contrast is added to unstained histological samples by using surface plasmon polaritons whose properties depend on the sample’s dielectric constant.

Eugeniu Balaur
Sandra O’ Toole
Brian Abbey
Research06 Oct 2021
Nature

Volume: 598, P: 65-71
Revealing excitation-inhibition imbalance in Alzheimer’s disease using multiscale neural model inversion of resting-state functional MRI

Li et al. apply a multiscale modeling approach to identify excitation-inhibition (E-I) imbalance in large scale neuronal circuits in Alzheimer’s disease (AD) based on functional MRI. E-I imbalance concentrates on the limbic and cingulate regions, and both local and long-range E-I balance is progressively disrupted from cognitively normal subjects to mild cognitive impairment, and to AD.

Guoshi Li
Li-Ming Hsu
Pew-Thian Yap
ResearchOpen Access15 Jan 2025
Communications Medicine

Volume: 5, P: 1-21
Correction: Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians

Ching-Yu Cheng
Kenji Yamashiro
Chiea Chuen Khor
Amendments and Corrections30 Mar 2015
Nature Communications

Volume: 6, P: 1
Profiling brain morphology for autism spectrum disorder with two cross-culture large-scale consortia

Using the lifespan brain chart and two large-scale cross-cultural consortia (ABIDE and CABIC), we disentangle the heterogeneity of brain morphology in ASD into two structural impairment pathways that could disrupt sensory to association functions.

Xue-Ru Fan
Ye He
Xi-Nian Zuo
ResearchOpen Access05 Aug 2025
Communications Biology

Volume: 8, P: 1-16
Lipofuscin of the retinal pigment epithelium: A review

Chris J Kennedy
Piroska E Rakoczy
Ian J Constable
Research01 Nov 1995
Eye

Volume: 9, P: 763-771
Mobile footprinting: linking individual distinctiveness in mobility patterns to mood, sleep, and brain functional connectivity

Cedric Huchuan Xia
Ian Barnett
Theodore D. Satterthwaite
Research03 Jun 2022
Neuropsychopharmacology

Volume: 47, P: 1662-1671
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola
Florian A. Karreth
David A. Tuveson
Research06 Jul 2011
Nature

Volume: 475, P: 106-109
Haemorrhagic pigment epithelial detachment as a predictive feature of polypoidal choroidal vasculopathy in a Chinese population

P Cackett
H Htoon
I Yeo
Research11 Sept 2009
Eye

Volume: 24, P: 789-792
Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

Morris Brown and colleagues identify somatic mutations in ATP1A1 and CACNA1D in aldosterone-producing adenomas with features resembling zonaglomerulosa cells. They further show that the ATP1A1 mutations cause inward leak currents under physiological conditions, whereas the CACNA1D mutations induce a shift of voltage-dependent gating to more negative potentials and suppress channel inactivation.

Elena A B Azizan
Hanne Poulsen
Morris J Brown
Research04 Aug 2013
Nature Genetics

Volume: 45, P: 1055-1060
Correction: Design, implementation, and evaluation of a nurse-led intravitreal injection programme for retinal diseases in Singapore

Alvin Wei Jun Teo
Tyler Hyungtaek Rim
Ian Yew San Yeo
Amendments and Corrections06 Jul 2020
Eye

Volume: 34, P: 2151
Comparison between MRI and pathology in the assessment of tumour regression grade in rectal cancer

Francesco Sclafani
Gina Brown
Ian Chau
ResearchOpen Access21 Sept 2017
British Journal of Cancer

Volume: 117, P: 1478-1485
Base editing: advances and therapeutic opportunities

Base editing is emerging as a potential approach to treat genetic diseases through the introduction of single-nucleotide alterations in DNA and RNA. Here, Porto et al. provide an overview of DNA and RNA base editing, discuss recent advances in the development of these technologies and highlight promising therapeutic applications.

Elizabeth M. Porto
Alexis C. Komor
Gene W. Yeo
Reviews19 Oct 2020
Nature Reviews Drug Discovery

Volume: 19, P: 839-859
DYNAMIC cohort study evaluating metabolic predictors of influenza vaccine immune response in older adults

Sapna P. Sadarangani
Barnaby E. Young
Angela Chow
ResearchOpen Access01 Nov 2022
npj Vaccines

Volume: 7, P: 1-9
Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations

Elena Lopez-Knowles
Alex Pearson
Mitch Dowsett
ResearchOpen Access19 Dec 2018
British Journal of Cancer

Volume: 120, P: 247-255
Systemic, Ocular and Genetic Risk Factors for Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Singaporeans

Chui Ming Gemmy Cheung
Augustinus Laude
Tien Yin Wong
ResearchOpen Access25 Jan 2017
Scientific Reports

Volume: 7, P: 1-10
Preferences and willingness-to-pay for a blood pressure telemonitoring program using a discrete choice experiment

Ian Yi Han Ang
Yi Wang
Alex R. Cook
ResearchOpen Access25 Sept 2023
npj Digital Medicine

Volume: 6, P: 1-9
Functional Connectivity in Brain Networks Underlying Cognitive Control in Chronic Cannabis Users

Ian H Harding
Nadia Solowij
Murat Yücel
Research25 Apr 2012
Neuropsychopharmacology

Volume: 37, P: 1923-1933
A computational approach to analyzing climate strategies of cities pledging net zero

Siddharth Sachdeva
Angel Hsu
Elwin Lim
ResearchOpen Access26 Aug 2022
npj Urban Sustainability

Volume: 2, P: 1-11
RETRACTED ARTICLE: Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy

Q Tan
A M Joshua
I F Tannock
ResearchOpen Access03 Feb 2015
British Journal of Cancer

Volume: 112, P: 832-840
Association between pet ownership and physical activity levels, atopic conditions, and mental health in Singapore: a propensity score-matched analysis

Ying Xian Goh
Joel Shi Quan Tan
Mun Yike Fiona Yee
ResearchOpen Access16 Nov 2020
Scientific Reports

Volume: 10, P: 1-13
Shared genetic variants for polypoidal choroidal vasculopathy and typical neovascular age-related macular degeneration in East Asians

Qiao Fan
Chui Ming Gemmy Cheung
Ching-Yu Cheng
Research24 Aug 2017
Journal of Human Genetics

Volume: 62, P: 1049-1055
Publisher Correction: Association between pet ownership and physical activity levels, atopic conditions, and mental health in Singapore: a propensity score-matched analysis

Ying Xian Goh
Joel Shi Quan Tan
Mun Yike Fiona Yee
Amendments and CorrectionsOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1
A longitudinal resource for population neuroscience of school-age children and adolescents in China

Xue-Ru Fan
Yin-Shan Wang
Xi-Nian Zuo
ResearchOpen Access21 Aug 2023
Scientific Data

Volume: 10, P: 1-24

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