Nature Search

Author Correction: Macrophages excite muscle spindles with glutamate to bolster locomotion

Yuyang Yan
Nuria Antolin
Simone Di Giovanni
Amendments and CorrectionsOpen Access21 Aug 2025
Nature

Volume: 645, P: E4
Macrophages excite muscle spindles with glutamate to bolster locomotion

A population of macrophages with exclusive molecular and functional signatures in the muscle spindles express machinery for synthesizing and releasing glutamate, and a cellular component, the muscle spindle macrophages, directly regulates neural activity and muscle contraction.

Yuyang Yan
Nuria Antolin
Simone Di Giovanni
ResearchOpen Access04 Dec 2024
Nature

Volume: 637, P: 698-707
Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons

This manuscript describes the systematic investigation of epigenomic signatures discriminating between regenerative success and failure in dorsal root ganglia sensory neurons following axonal injury. This epigenomic map offers a tool to design novel approaches for neuronal repair.

Ilaria Palmisano
Matt C. Danzi
Simone Di Giovanni
Research07 Oct 2019
Nature Neuroscience

Volume: 22, P: 1913-1924
Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling

Pre conditioning injury or environmental enrichment have been shown to promote axon regeneration. Here the authors show that environmental enrichment, combined with preconditioning injury promotes regeneration via a redox signalling dependent mechanism.

Francesco De Virgiliis
Thomas H. Hutson
Simone Di Giovanni
ResearchOpen Access21 Dec 2020
Nature Communications

Volume: 11, P: 1-16
AMPK controls the axonal regenerative ability of dorsal root ganglia sensory neurons after spinal cord injury

Whereas peripheral axons regenerate well after injury, axons located in the central nervous system, such as in the spinal cord, do not. Kong et al. identify AMPK as a regulator of neuronal regeneration and show that deletion of AMPKα1 promotes regeneration of injured spinal cord axons in mice.

Guiping Kong
Luming Zhou
Simone Di Giovanni
Research10 Aug 2020
Nature Metabolism

Volume: 2, P: 918-933
Publisher Correction: Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Arnau Hervera
Francesco De Virgiliis
Simone Di Giovanni
Amendments and Corrections08 Mar 2018
Nature Cell Biology

Volume: 20, P: 1098
Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Hervera et al. show that extracellular vesicles containing NOX2 complexes are released from macrophages and incorporated into injured axons, leading to axonal regeneration through PI3K–p-Akt signalling.

Arnau Hervera
Francesco De Virgiliis
Simone Di Giovanni
Research12 Feb 2018
Nature Cell Biology

Volume: 20, P: 307-319
TMS-EEG perturbation biomarkers for Alzheimer’s disease patients classification

Alexandra-Maria Tăuƫan
Elias P. Casula
Emiliano Santarnecchi
ResearchOpen Access11 May 2023
Scientific Reports

Volume: 13, P: 1-13

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