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Showing 1–5 of 5 results

Advanced filters: Author: Ilse Dewachter Clear advanced filters

GSK-3α/β kinases and amyloid production in vivo

Tomasz Jaworski
Ilse Dewachter
Fred Van Leuven
Research07 Dec 2011
Nature

Volume: 480, P: E4-E5
APOE deficiency inhibits amyloid-facilitated (A) tau pathology (T) and neurodegeneration (N), halting progressive ATN pathology in a preclinical model

Sarah Vanherle
Art Janssen
Ilse Dewachter
ResearchOpen Access30 Apr 2025
Molecular Psychiatry

Volume: 30, P: 4512-4528
Tau association with synaptic vesicles causes presynaptic dysfunction

Mislocalisation of tau occurs in several neurodegenerative diseases and is thought to contribute to synaptic function. The authors show that presynaptically, tau binds to synaptic vesicles via the N-terminus which contributes to synaptic dysfunction.

Lujia Zhou
Joseph McInnes
Patrik Verstreken
ResearchOpen Access11 May 2017
Nature Communications

Volume: 8, P: 1-13
Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model

Jeroen Bogie
Cindy Hoeks
Monique Mulder
ResearchOpen Access20 Mar 2019
Scientific Reports

Volume: 9, P: 1-16
Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

Anna Doshina
Florian Gourgue
Nathalie Pierrot
ResearchOpen Access23 Mar 2017
Scientific Reports

Volume: 7, P: 1-14