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Showing 1–4 of 4 results
Advanced filters: Author: Ilse S. Daehn Clear advanced filters

  • The inclusion of individuals with disabilities and patients as partners in biomedical research is critical for driving innovation. Equally important are patient–researchers, who are instrumental in identifying key research problems and driving research towards areas of direct benefit. We call for institutions to actively work towards accommodating patient–researchers.

    • Jonathan Haydak
    • Jacob Wright
    • Ilse S. Daehn
    Comments & Opinion
    Nature Reviews Nephrology
    Volume: 21, P: 362-363

  • Numerous kidney diseases are characterized by a breakdown of the glomerular filtration barrier, which forms the interface between the blood and urine. In this Review, Daehn and Duffield discuss strategies to target components of this barrier, focusing on mechanisms to control mitochondrial function and the actin–myosin machinery, to improve kidney function in individuals with kidney diseases.

    • Ilse S. Daehn
    • Jeremy S. Duffield
    Reviews
    Nature Reviews Drug Discovery
    Volume: 20, P: 770-788

  • More than three-quarters of cases of chronic kidney disease are caused by glomerular diseases with glomerulosclerosis, including diabetic kidney disease, hypertensive nephropathy and glomerulonephritis. Studies in 2022 provided insights into the molecular mechanisms that maintain dynamic glomerular structures and the responses of specific glomerular cell types during glomerular disease.

    • Emelie Lassén
    • Ilse S. Daehn
    News & Views
    Nature Reviews Nephrology
    Volume: 19, P: 85-86