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Showing 1–4 of 4 results
Advanced filters: Author: Imre Kacskovics Clear advanced filters

  • During embryonic development, neural progenitor cells undergo numerous cell divisions. Here, the authors show that ABHD4-mediated developmental anoikis distinguishes the physiological delamination and the pathological detachment of progenitor cells with relevance to fetal alcohol-induced apoptosis.

    • Zsófia I. László
    • Zsolt Lele
    • István Katona
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • Combining patch-clamp recordings and subsequent STORM imaging of individual cells, the authors show that the axon terminals of perisomatically- and dendritically-projecting GABAergic interneurons show differences in CB1 receptor number, active zone complexity, and receptor:effector ratio. Chronic exposure to THC evoked a dose-dependent and long-lasting downregulation of CB1 at these synapses.

    • Barna Dudok
    • László Barna
    • István Katona
    Research
    Nature Neuroscience
    Volume: 18, P: 75-86

  • Ca2+ release-activated Ca2+(CRAC) channels are essential for protective immunity, but the immunological functions of the three ORAI homologues that form CRAC channels are unclear. Here the authors show that ORAI1 and ORAI2 form heteromeric CRAC channels, which fine-tune T cell activation and immune responses.

    • Martin Vaeth
    • Jun Yang
    • Stefan Feske
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-17