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Advanced filters: Author: Indira Singaram Clear advanced filters
  • A small molecule was developed that disrupted the lipid–SH2 domain interaction of the spleen tyrosine kinase (Syk), suppressed oncogenic activities in acute myeloid leukemia cell lines and was refractory to drug resistance.

    • Indira Singaram
    • Ashutosh Sharma
    • Wonhwa Cho
    Research
    Nature Chemical Biology
    Volume: 19, P: 239-250