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Showing 1–2 of 2 results
Advanced filters: Author: Irene Maria Aspalter Clear advanced filters
  • Notch signals are crucial for organization of angiogenic sprouting cells into the leading ‘tip’ and trailing ‘stalk’ cells. Here the authors show that endothelial neuropilin-1 quantitatively inhibits TGF-β/BMP signalling, explaining how Notch-mediated regulation of neuropilin-1 specifies endothelial tip and stalk cells.

    • Irene Maria Aspalter
    • Emma Gordon
    • Holger Gerhardt
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13
  • The Haplobank contains over 100,000 individually reversibly mutagenized, barcoded, mouse embryonic cell lines; proof-of-principle experiments were used to search for genes that are required for rhinovirus infection and angiogenesis using forward and reverse genetic screens, respectively.

    • Ulrich Elling
    • Reiner A. Wimmer
    • Josef M. Penninger
    Research
    Nature
    Volume: 550, P: 114-118