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Advanced filters: Author: Isabelle Lamrissi-Garcia Clear advanced filters

  • CRISPR-Cas9 has been rapidly adopted to generate cell line models of disease. Here the authors show, while attempting to establish a congenital erythropoietic porphyria model, unexpected chromosome truncations generated by a p53-dependent mechanism.

    • Grégoire Cullot
    • Julian Boutin
    • Aurélie Bedel
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14