Nature Search

Stable restoration of the sarcoglycan complex in dystrophic muscle perfused with histamine and a recombinant adeno-associated viral vector

James P. Greelish
Leonard T. Su
Hansell H. Stedman
Research01 Apr 1999
Nature Medicine

Volume: 5, P: 439-443
Trust in scientists and their role in society across 68 countries

What is the state of trust in scientists around the world? To answer this question, the authors surveyed 71,922 respondents in 68 countries and found that trust in scientists is moderately high.

Viktoria Cologna
Niels G. Mede
Rolf A. Zwaan
ResearchOpen Access20 Jan 2025
Nature Human Behaviour

Volume: 9, P: 713-730
Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy

Missense variants in RNA-binding proteins underlie many diseases. Here the authors report an oculopharyngeal muscular dystrophy caused by heterozygous frameshift mutations in HNRNPA2B1 that alter its nucleocytoplasmic transport dynamics and result in cytoplasmic accumulation of hnRNPA2 protein.

Hong Joo Kim
Payam Mohassel
J. Paul Taylor
ResearchOpen Access28 Apr 2022
Nature Communications

Volume: 13, P: 1-18
RNase III CLASH in MRSA uncovers sRNA regulatory networks coupling metabolism to toxin expression

Regulatory small RNA (sRNA) interact with mRNAs to regulate their stability, transcription, and translation via diverse mechanisms. Here, McKellar et al. apply RNase IIICLASH of multi-drug resistant Staphylococcus aureus under different culture conditions to link the network of RNA-RNA interactions to environmental conditions and find that the production of small membrane-permeabilizing toxins is strongly regulated by sRNAs.

Stuart W. McKellar
Ivayla Ivanova
Sander Granneman
ResearchOpen Access22 Jun 2022
Nature Communications

Volume: 13, P: 1-20
Oak genome reveals facets of long lifespan

Oaks can live hundreds of years. Comparative genomics using a high-quality genome sequence provides new insights that may explain tree longevity. Samples from branches and corresponding acorns also help quantify heritable somatic mutations.

Christophe Plomion
Jean-Marc Aury
Jérôme Salse
ResearchOpen Access18 Jun 2018
Nature Plants

Volume: 4, P: 440-452
Reproducing plant microbiome research reveals site and time as key drivers of apple tree phyllosphere bacterial communities

Sophie Boutin
Isabelle Laforest-Lapointe
ResearchOpen Access15 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
The gut microbiome-prostate cancer crosstalk is modulated by dietary polyunsaturated long-chain fatty acids

Here, using murine models of prostate cancer, the authors show that reduced fecal microbiota alpha-diversity correlates with increased prostate tumor burden, and that Omega-3 prebiotic supplementation reduces prostate cancer up-grading associated with a reduction of gut Ruminococcaceae and fecal butyrate levels.

Gabriel Lachance
Karine Robitaille
Vincent Fradet
ResearchOpen Access23 Apr 2024
Nature Communications

Volume: 15, P: 1-15
Constitutional variants are not associated with HER2-positive breast cancer: results from the SIGNAL/PHARE clinical cohort

Xavier Pivot
Gilles Romieu
David G. Cox
ResearchOpen Access23 Feb 2017
npj Breast Cancer

Volume: 3, P: 1-5
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
A transcribed enhancer dictates mesendoderm specification in pluripotency

Long noncoding RNAs (lncRNAs) are key regulators of lineage specification during development. Here, the authors investigate remodeling of enhancers and regulation of the lncRNA transcriptome during mesendoderm specification, and identify a pluripotent stage-specific transcribed enhancer controlling adoption of the mesendodermal cell fate.

Michael Alexanian
Daniel Maric
Thierry Pedrazzini
ResearchOpen Access27 Nov 2017
Nature Communications

Volume: 8, P: 1-19
Academic research sheds light on issues that matter to patients

In 2015, academic-led trials provided evidence for safe de-escalation of adjuvant treatment in early stage breast cancer and answered important questions related to adjuvant regional irradiation and optimal first-line chemotherapy in advanced-stage disease. Furthermore, the development of novel therapies and potential tools for treatment tailoring will offer new hope to patients with breast cancer.

Martine J. Piccart
Isabelle Gingras
News & Views20 Jan 2016
Nature Reviews Clinical Oncology

Volume: 13, P: 67-68
Parental burnout and borderline personality stand out to predict child maltreatment

Alice Schittek
Isabelle Roskam
Moïra Mikolajczak
ResearchOpen Access27 Jul 2023
Scientific Reports

Volume: 13, P: 1-6
Two genomes of highly polyphagous lepidopteran pests (Spodoptera frugiperda, Noctuidae) with different host-plant ranges

Anaïs Gouin
Anthony Bretaudeau
Philippe Fournier
ResearchOpen Access25 Sept 2017
Scientific Reports

Volume: 7, P: 1-12
Rescuing cellular function in Fuchs endothelial corneal dystrophy by healthy exogenous mitochondrial internalization

Sébastien Méthot
Stéphanie Proulx
Patrick J. Rochette
ResearchOpen Access28 Feb 2023
Scientific Reports

Volume: 13, P: 1-10
SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma

Here, in a mouse model of skin squamous cell carcinoma, a key role is demonstrated for the transcription factor SOX2 in the initiation and progression of skin tumours.

Soufiane Boumahdi
Gregory Driessens
Cédric Blanpain
Research08 Jun 2014
Nature

Volume: 511, P: 246-250
Long-term outcome of imatinib 400 mg compared to imatinib 600 mg or imatinib 400 mg daily in combination with cytarabine or pegylated interferon alpha 2a for chronic myeloid leukaemia: results from the French SPIRIT phase III randomised trial

Francois Guilhot
Françoise Rigal-Huguet
Franck-Emmanuel Nicolini
Research22 Jan 2021
Leukemia

Volume: 35, P: 2332-2345
IGF-IR: a new prognostic biomarker for human glioblastoma

C Maris
N D'Haene
I Salmon
ResearchOpen Access20 Aug 2015
British Journal of Cancer

Volume: 113, P: 729-737
Genetic and clinical specificity of 26 symptomatic carriers for dystrophinopathies at pediatric age

Sandra Mercier
Annick Toutain
Isabelle Desguerre
Research09 Jan 2013
European Journal of Human Genetics

Volume: 21, P: 855-863
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer’s disease

Alexandre Poirier
Cynthia Picard
Judes Poirier
ResearchOpen Access26 Jun 2024
Scientific Reports

Volume: 14, P: 1-13
Perceptions of science, science communication, and climate change attitudes in 68 countries – the TISP dataset

Niels G. Mede
Viktoria Cologna
Rolf A. Zwaan
ResearchOpen Access20 Jan 2025
Scientific Data

Volume: 12, P: 1-27
An experimental manipulation of cognitive appraisals in parental burnout

Aline Woine
Dorota Szczygiel
Moïra Mikolajczak
ResearchOpen Access18 Jul 2023
Scientific Reports

Volume: 13, P: 1-11
iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities

Hugo Poulin
Aurélie Mercier
Mohamed Chahine
ResearchOpen Access28 Jan 2021
Scientific Reports

Volume: 11, P: 1-13
Resting-state MRI functional connectivity as a neural correlate of multidomain lifestyle adherence in older adults at risk for Alzheimer’s disease

Meishan Ai
Timothy P. Morris
Seqian Wang
ResearchOpen Access09 May 2023
Scientific Reports

Volume: 13, P: 1-14
Healthy mice with an altered c-myc gene: role of the 3′ untranslated region revisited

Francina Langa
Isabelle Lafon
Dominique Morello
Research19 Jul 2001
Oncogene

Volume: 20, P: 4344-4353
Test-retest resting-state fMRI in healthy elderly persons with a family history of Alzheimer’s disease

Pierre Orban
Cécile Madjar
Seqian Wang
ResearchOpen Access13 Oct 2015
Scientific Data

Volume: 2, P: 1-11

Search

Stable restoration of the sarcoglycan complex in dystrophic muscle perfused with histamine and a recombinant adeno-associated viral vector

Trust in scientists and their role in society across 68 countries

Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy

RNase III CLASH in MRSA uncovers sRNA regulatory networks coupling metabolism to toxin expression

Oak genome reveals facets of long lifespan

Reproducing plant microbiome research reveals site and time as key drivers of apple tree phyllosphere bacterial communities

The gut microbiome-prostate cancer crosstalk is modulated by dietary polyunsaturated long-chain fatty acids

Constitutional variants are not associated with HER2-positive breast cancer: results from the SIGNAL/PHARE clinical cohort

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

A transcribed enhancer dictates mesendoderm specification in pluripotency

Academic research sheds light on issues that matter to patients

Parental burnout and borderline personality stand out to predict child maltreatment

Two genomes of highly polyphagous lepidopteran pests (Spodoptera frugiperda, Noctuidae) with different host-plant ranges

Rescuing cellular function in Fuchs endothelial corneal dystrophy by healthy exogenous mitochondrial internalization

SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma

Long-term outcome of imatinib 400 mg compared to imatinib 600 mg or imatinib 400 mg daily in combination with cytarabine or pegylated interferon alpha 2a for chronic myeloid leukaemia: results from the French SPIRIT phase III randomised trial

IGF-IR: a new prognostic biomarker for human glioblastoma

Genetic and clinical specificity of 26 symptomatic carriers for dystrophinopathies at pediatric age

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer’s disease

Perceptions of science, science communication, and climate change attitudes in 68 countries – the TISP dataset

An experimental manipulation of cognitive appraisals in parental burnout

iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities

Resting-state MRI functional connectivity as a neural correlate of multidomain lifestyle adherence in older adults at risk for Alzheimer’s disease

Healthy mice with an altered c-myc gene: role of the 3′ untranslated region revisited

Test-retest resting-state fMRI in healthy elderly persons with a family history of Alzheimer’s disease

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