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Showing 1–4 of 4 results
Advanced filters: Author: Isabelle Pachmayr Clear advanced filters

  • By combining left- and right-handed DNA-PAINT probes, Unterauer et al. achieve simple, robust, and highly multiplexed super-resolution. They show 13-plex neuronal maps, revealing nanoscale organization of cytoskeleton, organelles, and synapses.

    • Eduard M. Unterauer
    • Eva-Maria Schentarra
    • Ralf Jungmann
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-8

  • The nanoscale organization of the antigen-antibody complexes influences the therapeutic action of monoclonal antibodies. Here, the authors present a multi-target 3D RESI imaging assay for the nanometer spatial analysis of CD20 in complex with therapeutic monoclonal antibodies within intact cells, to analyse the interdependency between the mode of antibody binding and the therapeutic function.

    • Isabelle Pachmayr
    • Luciano A. Masullo
    • Ralf Jungmann
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • By combining bioorthogonal metabolic labelling and resolution enhancement through sequential imaging of DNA barcodes, the molecular organization of individual sugars in the native glycocalyx has been resolved at a spatial resolution of 9 ångström.

    • Luciano A. Masullo
    • Karim Almahayni
    • Leonhard Möckl
    ResearchOpen Access
    Nature Nanotechnology
    P: 1-7

  • Extracting quantitative information on biomolecular oligomerisation with high resolution remains a significant challenge. Here, the authors propose SPINNA, a framework that compares nearest-neighbour distances from experimental single-protein position data with those obtained from simulations based on a model of protein oligomerisation.

    • Luciano A. Masullo
    • Rafal Kowalewski
    • Ralf Jungmann
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11