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Showing 1–3 of 3 results
Advanced filters: Author: Isabelle Riezman Clear advanced filters
  • Enkler et al. show that a pool of Arf1 at lipid droplets is implicated in mitochondrial ATP production control through regulation of fatty acid metabolism and acetyl-CoA transfer to mitochondria.

    • Ludovic Enkler
    • Viktoria Szentgyörgyi
    • Anne Spang
    ResearchOpen Access
    Nature Cell Biology
    Volume: 25, P: 1157-1172
  • The lipid content of the plasma membrane is dynamically regulated to maintain cellular homeostasis, but the molecular links between membrane stress and sphingolipid synthesis have remained elusive. Walther, Loewith and colleagues report that membrane stretching causes redistribution of Slm proteins, which then promote sphingolipid synthesis through activation of the TORC2–Ypk signalling pathway.

    • Doris Berchtold
    • Manuele Piccolis
    • Robbie Loewith
    Research
    Nature Cell Biology
    Volume: 14, P: 542-547
  • VPS15 is known as a VPS34-associated protein that functions in intracellular trafficking and autophagy. Here the authors identify a role for VPS15 in ciliopathy and ciliary phenotypes, and show that it interacts with GM130 and functions in IFT20-dependent cis-Golgi to cilium trafficking.

    • Corinne Stoetzel
    • Séverine Bär
    • Hélène Dollfus
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-13