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Showing 1–4 of 4 results

Advanced filters: Author: Isabelle Scheyltjens Clear advanced filters

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Single-cell RNA-seq and CITE-seq were used to profile the glioblastoma immune landscape in humans and mice, revealing the diversity and dynamics of tumor macrophages as the disease progresses from initial diagnosis to recurrence.

Ana Rita Pombo Antunes
Isabelle Scheyltjens
Kiavash Movahedi
Research29 Mar 2021
Nature Neuroscience

Volume: 24, P: 595-610
Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues

This protocol enables single-cell multi-omic analysis of the mouse brain immune compartment to explore immune cell heterogeneity and activation in the healthy and diseased brain, using a workflow based on HD flow cytometry, scRNA-seq and CITE-seq.

Isabelle Scheyltjens
Hannah Van Hove
Kiavash Movahedi
Protocols05 Aug 2022
Nature Protocols

Volume: 17, P: 2354-2388
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Van Hove et al. reveal the diversity of macrophages at the brain’s border regions via single-cell analysis and fate-mapping. This also identified a microglial subset at the surface of the choroid plexus, in direct contact with cerebrospinal fluid.

Hannah Van Hove
Liesbet Martens
Kiavash Movahedi
Research06 May 2019
Nature Neuroscience

Volume: 22, P: 1021-1035
c-Fos expression following context conditioning and deep brain stimulation in the bed nucleus of the stria terminalis in rats

Kelly Luyck
Isabelle Scheyltjens
Laura Luyten
ResearchOpen Access25 Nov 2020
Scientific Reports

Volume: 10, P: 1-12