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Optimization of nucleophilic ¹⁸F radiofluorinations using a microfluidic reaction approach

A quick route towards new radiofluorinated tracers is important for the development of PET imaging. An efficient, reliable method for optimizing radiofluorination conditions using a microfluidic chemistry approach is described in this protocol.

Giancarlo Pascali
Lidia Matesic
Ivan Greguric
Protocols31 Jul 2014
Nature Protocols

Volume: 9, P: 2017-2029

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Optimization of nucleophilic 18F radiofluorinations using a microfluidic reaction approach

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Optimization of nucleophilic ¹⁸F radiofluorinations using a microfluidic reaction approach