Nature Search

Global impoverishment of natural vegetation revealed by dark diversity

A comparison of alpha diversity (number of plant species) and dark diversity (species that are currently absent from a site despite being ecologically suitable) demonstrates the negative effects of regional-scale anthropogenic activity on plant diversity.

Meelis Pärtel
Riin Tamme
Martin Zobel
ResearchOpen Access02 Apr 2025
Nature

Volume: 641, P: 917-924
Amorphous oxide precipitates in silicon single crystals

S. Messoloras
J. R. Schneider
W. Zulehner
Research24 Nov 1988
Nature

Volume: 336, P: 364-365
Organographie der Pflanzen insbesondere der Archegoniaten und Samenpflanzen

J. B. FARMER
Books & Arts15 May 1902
Nature

Volume: 66, P: 51
Caenorhabditis elegans expressed sequence tags identify gene families and potential disease gene homologues

W. Richard McCombie
Mark D. Adams
Chris Fields
Research01 May 1992
Nature Genetics

Volume: 1, P: 124-131
A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria

Christopher F. Higgins
Ian D. Hiles
Mark A. Hermodson
Research02 Oct 1986
Nature

Volume: 323, P: 448-450
A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice

Michael R. Kuehn
Allan Bradley
Martin J. Evans
Research25 Mar 1987
Nature

Volume: 326, P: 295-298
PI3Kβ controls immune evasion in PTEN-deficient breast tumours

A mouse model of invasive breast cancer in which Pten and Trp53 are simultaneously inactivated links PTEN loss with STAT3 activation and indicates that immune escape in PTEN-null tumours is mediated by PI3Kβ.

Johann S. Bergholz
Qiwei Wang
Jean J. Zhao
Research19 Apr 2023
Nature

Volume: 617, P: 139-146
STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer

PARP inhibitor (PARPi) therapy has demonstrated only modest efficacy in advanced breast cancer with BRCA mutations. Here the authors show that, by suppressing PARPi-triggered DNA damage and reducing dsDNA production in BRCA1-deficient breast tumor cells, tumor associated macrophages contribute to PARPi resistance, that can be overcome by STING agonism.

Qiwei Wang
Johann S. Bergholz
Jean J. Zhao
ResearchOpen Access31 May 2022
Nature Communications

Volume: 13, P: 1-17
Physical deformities relevant to male infertility

In this thorough and comprehensive Review, Singh and colleagues describe a number of physical deformities associated with the testes, scrotum, epididymis, vasa deferentia, ejaculatory ducts and prostate that either commonly occur in infertile men or are potentially associated with male infertility. They include brief outlines of the available treatment options.

Rajender Singh
Alaa J. Hamada
Ashok Agarwal
Reviews21 Feb 2012
Nature Reviews Urology

Volume: 9, P: 156-174
Temporal and spatial topography of cell proliferation in cancer

Gaglia, Kabraji and colleagues quantify cell cycle markers in single cells to define the spatial distribution of proliferation in tumours. They define metrics that capture clinically significant features of cancer proliferation.

Giorgio Gaglia
Sheheryar Kabraji
Sandro Santagata
Research15 Mar 2022
Nature Cell Biology

Volume: 24, P: 316-326
Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model

L. Berrueta
J. Bergholz
H. M. Langevin
ResearchOpen Access18 May 2018
Scientific Reports

Volume: 8, P: 1-7
Automated high resolution PCR fragment analysis for identification of clonally rearranged immunoglobulin heavy chain genes

B Linke
I Bolz
M Kneba
Research01 Jul 1997
Leukemia

Volume: 11, P: 1055-1062
The role of soluble growth factors in inducing transient growth and clonal extinction of stroma cell dependent erythroblastic leukemia cells

K Itoh
J Friel
W Ostertag
Research01 Oct 1997
Leukemia

Volume: 11, P: 1753-1761
Bacterial growth at −15 °C; molecular insights from the permafrost bacterium Planococcus halocryophilus Or1

Nadia C S Mykytczuk
Simon J Foote
Lyle G Whyte
Research07 Feb 2013
The ISME Journal

Volume: 7, P: 1211-1226
The influence of survey duration on estimates of food intakes and its relevance for public health nutrition and food safety issues

J Lambe
J Kearney
MJ Gibney
Research23 Feb 2000
European Journal of Clinical Nutrition

Volume: 54, P: 166-173
Targeting CDK4 and CDK6 in cancer

Dysregulation of cyclin-dependent kinase 4 (CDK4) and CDK6, regulators of the cell cycle, favours the growth and survival of several cancer types. Owing to this, CDK4 and CDK6 inhibitors were developed and are currently approved for the treatment of advanced hormone receptor-positive breast cancer. This Review describes how we are only now beginning to fully understand their mechanisms of action and provides a new framework for conceptualizing their activity, which might enable expansion of the clinical opportunities of these agents.

Shom Goel
Johann S. Bergholz
Jean J. Zhao
Reviews18 Mar 2022
Nature Reviews Cancer

Volume: 22, P: 356-372
Survival of Escherichia coli in the environment: fundamental and public health aspects

Jan Dirk van Elsas
Alexander V Semenov
Jack T Trevors
Reviews24 Jun 2010
The ISME Journal

Volume: 5, P: 173-183
Author Correction: Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model

L. Berrueta
J. Bergholz
H. M. Langevin
Amendments and CorrectionsOpen Access16 Nov 2018
Scientific Reports

Volume: 8, P: 1
Expression of a suppressive p15E-related epitope in colorectal and gastric cancer

S Foulds
CH Wakefield
PJ Guillou
Research01 Sept 1993
British Journal of Cancer

Volume: 68, P: 610-616
Induction of reactive oxygen intermediates in human monocytes by tumour cells and their role in spontaneous monocyte cytotoxicity

B Mytar
M Siedlar
M Zembala
ResearchOpen Access29 Jan 1999
British Journal of Cancer

Volume: 79, P: 737-743
Bacterial genome replication at subzero temperatures in permafrost

Steven J Tuorto
Phillip Darias
Lee J Kerkhof
Research29 Aug 2013
The ISME Journal

Volume: 8, P: 139-149
Nicotine reduces discrimination between threat and safety in the hippocampus, nucleus accumbens and amygdala

Madeleine Mueller
Tahmine Fadai
Jan Haaker
ResearchOpen Access03 Aug 2024
Translational Psychiatry

Volume: 14, P: 1-10
ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion

J Wu
S Liang
Z-X Xiao
ResearchOpen Access05 Jun 2014
Cell Death & Disease

Volume: 5, P: e1280
Acquisition of threat responses are associated with elevated plasma concentration of endocannabinoids in male humans

Smilla Weisser
Madeleine Mueller
Jan Haaker
ResearchOpen Access13 May 2022
Neuropsychopharmacology

Volume: 47, P: 1931-1938
NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K–AKT and JAK–STAT3 pathways

Haluk Yuzugullu
Thanh Von
Jean J Zhao
ResearchOpen Access20 Sept 2016
Cell Discovery

Volume: 2, P: 1-13
ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

J Bergholz
Y Zhang
Z-X Jim Xiao
Research17 Dec 2012
Oncogene

Volume: 33, P: 212-224
Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells

S Horn
U Bergholz
J Bäsecke
Research03 Mar 2008
Oncogene

Volume: 27, P: 4096-4106
Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage

Y Tong
H Ying
Z-X Xiao
ResearchOpen Access12 Feb 2015
Cell Death & Disease

Volume: 6, P: e1640
MDMX exerts its oncogenic activity via suppression of retinoblastoma protein

H Zhang
L Hu
Z-X Xiao
Research23 Feb 2015
Oncogene

Volume: 34, P: 5560-5569
Diet and hip fractures among elderly Europeans in the EPIC cohort

V Benetou
P Orfanos
A Trichopoulou
Research13 Oct 2010
European Journal of Clinical Nutrition

Volume: 65, P: 132-139
Investigation of C/EBPα function in human (versus murine) myelopoiesis provides novel insight into the impact of CEBPA mutations in acute myelogenous leukemia (AML)

B Niebuhr
G B Iwanski
J Cammenga
Correspondence20 Nov 2008
Leukemia

Volume: 23, P: 978-983
Role of SHP2 for FLT3-dependent proliferation and transformation in 32D cells

J P Müller
C Schönherr
F-D Böhmer
Correspondence27 Mar 2008
Leukemia

Volume: 22, P: 1945-1948

Search

Global impoverishment of natural vegetation revealed by dark diversity

Amorphous oxide precipitates in silicon single crystals

Organographie der Pflanzen insbesondere der Archegoniaten und Samenpflanzen

Caenorhabditis elegans expressed sequence tags identify gene families and potential disease gene homologues

A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria

A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice

PI3Kβ controls immune evasion in PTEN-deficient breast tumours

STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer

Physical deformities relevant to male infertility

Temporal and spatial topography of cell proliferation in cancer

Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model

Automated high resolution PCR fragment analysis for identification of clonally rearranged immunoglobulin heavy chain genes

The role of soluble growth factors in inducing transient growth and clonal extinction of stroma cell dependent erythroblastic leukemia cells

Bacterial growth at −15 °C; molecular insights from the permafrost bacterium Planococcus halocryophilus Or1

The influence of survey duration on estimates of food intakes and its relevance for public health nutrition and food safety issues

Targeting CDK4 and CDK6 in cancer

Survival of Escherichia coli in the environment: fundamental and public health aspects

Author Correction: Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model

Expression of a suppressive p15E-related epitope in colorectal and gastric cancer

Induction of reactive oxygen intermediates in human monocytes by tumour cells and their role in spontaneous monocyte cytotoxicity

Bacterial genome replication at subzero temperatures in permafrost

Nicotine reduces discrimination between threat and safety in the hippocampus, nucleus accumbens and amygdala

ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion

Acquisition of threat responses are associated with elevated plasma concentration of endocannabinoids in male humans

NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K–AKT and JAK–STAT3 pathways

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells

Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage

MDMX exerts its oncogenic activity via suppression of retinoblastoma protein

Diet and hip fractures among elderly Europeans in the EPIC cohort

Investigation of C/EBPα function in human (versus murine) myelopoiesis provides novel insight into the impact of CEBPA mutations in acute myelogenous leukemia (AML)

Role of SHP2 for FLT3-dependent proliferation and transformation in 32D cells

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