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Showing 151–200 of 300 results

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Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface

Bispecifics by orthogonal interfaces To improve correct antibody heavy-light chain pairing during bispecific antibody assembly, Lewis et al. design antibody heavy and light chains with orthogonal interfaces.

Steven M Lewis
Xiufeng Wu
Stephen J Demarest
Research26 Jan 2014
Nature Biotechnology

Volume: 32, P: 191-198
Disorder-specific alterations of tactile sensitivity in neurodevelopmental disorders

He et al. assessed different parameters of tactile processing in children diagnosed with autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). They found evidence for disorder-specific alterations of lower-level sensory processing, which can be related back to higher-level clinical symptoms.

Jason L. He
Ericka Wodka
Nicolaas A. J. Puts
ResearchOpen Access22 Jan 2021
Communications Biology

Volume: 4, P: 1-15
Genome sequence and analysis of the tuber crop potato

Xun Xu
Shengkai Pan
Richard G. F. Visser
ResearchOpen Access10 Jul 2011
Nature

Volume: 475, P: 189-195
Kainate receptor subunit 1 (GRIK1) risk variants and GRIK1 deficiency were detected in the Indian ADHD probands

Mahasweta Chatterjee
Sharmistha Saha
Kanchan Mukhopadhyay
ResearchOpen Access02 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
Bringing together population and quantitative genetics

J M Cano Arias
Books & Arts27 Jul 2005
Heredity

Volume: 95, P: 179-180
Intravenous nicardipine for Japanese patients with acute intracerebral hemorrhage: an individual participant data analysis

Kazunori Toyoda
Sohei Yoshimura
Kazuo Minematsu
ResearchOpen Access13 Oct 2022
Hypertension Research

Volume: 46, P: 75-83
Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

The mechanisms that govern the transdifferentiation of lung adenocarcinomas (ADC) to squamous cell carcinoma (SCC) are not fully understood. Here, the authors show that EZH2 loss exacerbates the transdifferentiation of ADCs to SCCs as a result of chromatin changes that lead to expression of squamous differentiation genes.

Haikuo Zhang
Christine Fillmore Brainson
Kwok-Kin Wong
ResearchOpen Access07 Apr 2017
Nature Communications

Volume: 8, P: 1-15
RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells

Hawk et al. show that RIPK1 activation during extracellular matrix detachment induces mitophagy through mitochondrial phosphatase PGAM5 to increase reactive oxygen species and non-apoptotic cell death, and that antagonizing RIPK1/PGAM5 enhances tumour formation.

Mark A. Hawk
Cassandra L. Gorsuch
Zachary T. Schafer
Research19 Feb 2018
Nature Cell Biology

Volume: 20, P: 272-284
DIABETES MELLITUS AND VASCULAR DISEASE: POSSIBLE ROLE OF HYDROXYACIDS IN ITS GENESIS

M Stuart
J Graeber
B Glaser
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 300
Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling

ATRX inactivation frequently occurs in glioma. Here, the authors explore the role of ATRX inactivation in oncogenesis, highlighting ATRX deficiency driven epigenomic changes that influence the expression of genes crucial to the oncogenic phenotype.

Carla Danussi
Promita Bose
Jason T. Huse
ResearchOpen Access13 Mar 2018
Nature Communications

Volume: 9, P: 1-15
Centrosome misorientation reduces stem cell division during ageing

Asymmetric division of adult stem cells generates one self-renewing stem cell and one differentiating cell, thereby maintaining tissue homeostasis. This paper shows that changes in stem cell orientation within the niche during ageing contribute to the decline in spermatogenesis in Drosophila male germ line.

Jun Cheng
Nezaket Türkel
Yukiko M. Yamashita
Research01 Dec 2008
Nature

Volume: 456, P: 599-604
Metagenomes and 1,313 metagenome-assembled genomes from a northern Gulf of Mexico coastal time series

Conner Y. Kojima
Michael W. Henson
J. Cameron Thrash
ResearchOpen Access08 Aug 2025
Scientific Data

Volume: 12, P: 1-10
Genetic constraints on floral evolution: a review and evaluation of patterns

T-L Ashman
C J Majetic
Reviews05 Apr 2006
Heredity

Volume: 96, P: 343-352
The homeobox gene mirror links EGF signalling to embryonic dorso-ventral axis formation through Notch activation

Katherine C. Jordan
Nigel J. Clegg
Hannele Ruohola-Baker
Research01 Apr 2000
Nature Genetics

Volume: 24, P: 429-433
Auditory rhythm facilitates perception and action in children at risk for developmental coordination disorder

Chantal Carrillo
Andrew Chang
Laurel J. Trainor
ResearchOpen Access28 May 2024
Scientific Reports

Volume: 14, P: 1-13
Genetic linkage of ecological specialization and reproductive isolation in pea aphids

David J. Hawthorne
Sara Via
Research30 Aug 2001
Nature

Volume: 412, P: 904-907
Chronic prenatal delta-9-tetrahydrocannabinol exposure adversely impacts placental function and development in a rhesus macaque model

Victoria H. J. Roberts
Matthias C. Schabel
Jamie O. Lo
ResearchOpen Access24 Nov 2022
Scientific Reports

Volume: 12, P: 1-11
A strategy for systemic delivery of the oncolytic herpes virus HSV1716: redirected tropism by antibody-binding sites incorporated on the virion surface as a glycoprotein D fusion protein

J Conner
L Braidwood
S M Brown
Research14 Aug 2008
Gene Therapy

Volume: 15, P: 1579-1592
An exploratory, pragmatic, cluster randomised trial of practice nurse training in the use of asthma action plans

Jennifer A Cleland
Susan Hall
Amanda J Lee
Research12 Oct 2007
Primary Care Respiratory Journal

Volume: 16, P: 311-318
The Ischian Earthquake

H. J. JOHNSTON-LAVIS
News09 Aug 1883
Nature

Volume: 28, P: 345-348
Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis

Elizabeth A Conner
Eric R Lemmer
Snorri S Thorgeirsson
Research19 Oct 2000
Oncogene

Volume: 19, P: 5054-5062
Characterization of the Coleopteran–Specific Protein Gene of Bacillus thuringiensis Var. tenebrionis

Sylvia A. McPherson
Frederick J. Perlak
David A. Fischhoff
Research01 Jan 1988
Bio/Technology

Volume: 6, P: 61-66
Inaccuracies of deterministic finite-element models of human middle ear revealed by stochastic modelling

Arash Ebrahimian
Hossein Mohammadi
Nima Maftoon
ResearchOpen Access05 May 2023
Scientific Reports

Volume: 13, P: 1-13
Crystal structure of a nucleosome core particle containing the variant histone H2A.Z

Robert K. Suto
Michael J. Clarkson
Karolin Luger
Research01 Dec 2000
Nature Structural Biology

Volume: 7, P: 1121-1124
Violating Bell’s inequality with remotely connected superconducting qubits

A deterministic violation of the Bell inequality is reported between two superconducting circuits, providing a necessary test for establishing strong enough quantum entanglement to achieve secure quantum communications.

Y. P. Zhong
H.-S. Chang
A. N. Cleland
Research22 Apr 2019
Nature Physics

Volume: 15, P: 741-744
Experimental evidence that shear bands in metallic glasses nucleate like cracks

Alan A. Long
Wendelin J. Wright
Karin A. Dahmen
ResearchOpen Access02 Nov 2022
Scientific Reports

Volume: 12, P: 1-10
842 BLUNTED MUSCLE RESPONSIVENESS TO INSULIN IN THE NEONATAL RAT

R M Cowett
M Czech
W Oh
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 504
MYCN and KAT2A form a feedforward loop to drive an oncogenic transcriptional program in neuroblastoma

Zhihui Liu
Jason J. Hong
Carol J. Thiele
ResearchOpen Access24 Apr 2025
Oncogenesis

Volume: 14, P: 1-13
Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis

Song-Tao Liu
James C. Hittle
Tim J. Yen
Research17 Mar 2003
Nature Cell Biology

Volume: 5, P: 341-345
[15N]LYSINE METABOLISM IN HYPOGLYCIN-TREATED RATS: EVIDENCE FOR THE SACCHAROPINE PATHWAY AS THE MAJOR PATHWAY IN VIVO

D Hyman
T Ito
K Tanaka
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 300
Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood

Ragna Bugge Askeland
Laurie J. Hannigan
Alexandra Havdahl
ResearchOpen Access23 Jun 2023
Translational Psychiatry

Volume: 13, P: 1-9
A common polymorphism in serotonin receptor 1B mRNA moderates regulation by miR-96 and associates with aggressive human behaviors

K P Jensen
J Covault
H M Furneaux
Research19 Feb 2008
Molecular Psychiatry

Volume: 14, P: 381-389
Cortical structural and functional coupling during development and implications for attention deficit hyperactivity disorder

Shania Mereen Soman
Nandita Vijayakumar
Timothy J. Silk
ResearchOpen Access11 Jul 2023
Translational Psychiatry

Volume: 13, P: 1-10
Continuous infusion or subcutaneous injection of granulocyte-macrophage colony-stimulating factor: increased efficacy and reduced toxicity when given subcutaneously

AH Honkoop
K Hoekman
HM Pinedo
Research01 Oct 1996
British Journal of Cancer

Volume: 74, P: 1132-1136
Primary gastrointestinal non-Hodgkin's lymphoma in a population-based registry

R Otter
R Bieger
R Willemze
Research01 Nov 1989
British Journal of Cancer

Volume: 60, P: 745-750
Prevalence of overweight and central adiposity is associated with percentage of indigenous ancestry among native Hawaiians

A Grandinetti
HK Chang
J David Curb
Research10 Aug 1999
International Journal of Obesity

Volume: 23, P: 733-737
Neural mechanisms underlying rule selection based on response evaluation: a near-infrared spectroscopy study

Taeko Harada
Toshiki Iwabuchi
Yoko Hoshi
ResearchOpen Access30 Nov 2022
Scientific Reports

Volume: 12, P: 1-11
Deep learning enables accurate soft tissue tendon deformation estimation in vivo via ultrasound imaging

Reece D. Huff
Frederick Houghton
Grace D. O’Connell
ResearchOpen Access08 Aug 2024
Scientific Reports

Volume: 14, P: 1-11
Acute intermittent porphyria: novel missense mutations in the human hydroxymethylbilane synthase gene

Risha B Ramdall
Luis Cunha
Robert J Desnick
Research01 Sept 2000
Genetics in Medicine

Volume: 2, P: 290-295
Altered neural flexibility in children with attention-deficit/hyperactivity disorder

Weiyan Yin
Tengfei Li
Weili Lin
ResearchOpen Access22 Jul 2022
Molecular Psychiatry

Volume: 27, P: 4673-4679
Effects of a low-head weir on multi-scaled movement and behavior of three riverine fish species

Luke Carpenter-Bundhoo
Gavin L. Butler
Mark J. Kennard
ResearchOpen Access22 Apr 2020
Scientific Reports

Volume: 10, P: 1-14
Influence of the desire to lose weight on food habits, and knowledge of the characteristics of a balanced diet, in a group of Madrid university students

B Navia
R M Ortega
A M López-Sobaler
Research28 Aug 2003
European Journal of Clinical Nutrition

Volume: 57, P: S90-S93
Shared and distinct resting functional connectivity in children and adults with attention-deficit/hyperactivity disorder

Xiaojie Guo
Dongren Yao
Li Sun
ResearchOpen Access12 Feb 2020
Translational Psychiatry

Volume: 10, P: 1-12
The dopamine transporter gene is associated with attention deficit hyperactivity disorder in a Taiwanese sample

C-K Chen
S-L Chen
P Asherson
Research09 May 2003
Molecular Psychiatry

Volume: 8, P: 393-396
Regulation of the Drosophila apoptosome through feedback inhibition

The apoptotic inhibitor IAP1 regulates a feedback loop between the caspase Dronc1 and its apoptosome adaptor Apaf1 to maintain low caspase activity in cells that are not destined to die.

Peter J. Shapiro
Hans H. Hsu
Hyung Don Ryoo
Research16 Nov 2008
Nature Cell Biology

Volume: 10, P: 1440-1446
Use of dietary supplements in the European Prospective Investigation into Cancer and Nutrition calibration study

G Skeie
T Braaten
N Slimani
Research04 Nov 2009
European Journal of Clinical Nutrition

Volume: 63, P: S226-S238
Pursuing a scientific career with ADHD

Attention deficit hyperactivity disorder presents considerable barriers to a successful research career. Universities need to start taking this into account to ensure that talented researchers are retained in the sector and given an equal opportunity to succeed.

James E. Brown
Comments & Opinion21 Mar 2022
Nature Reviews Endocrinology

Volume: 18, P: 325-326
Psychosocial effects in parents and children 12 years after newborn genetic screening for type 1 diabetes

Nicola J Kerruish
Dione M Healey
Andrew R Gray
Research25 Jan 2017
European Journal of Human Genetics

Volume: 25, P: 397-403
The genetic basis of divergent pigment patterns in juvenile threespine sticklebacks

A K Greenwood
F C Jones
C L Peichel
Research09 Feb 2011
Heredity

Volume: 107, P: 155-166
Automated and virus variant-programmable surrogate test qualitatively compares to the gold standard SARS-CoV-2 neutralization assay

Danielle W. Ali
Maggie L. Bartlett
Darci R. Smith
ResearchOpen Access30 Dec 2024
npj Viruses

Volume: 2, P: 1-8

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