Nature Search

Naturally Occurring Alpha-Activity of Drinking Waters

R. C. TURNER
J. M. RADLEY
W. V. MAYNEORD
Research04 Feb 1961
Nature

Volume: 189, P: 348-352
Neutralizing and binding antibodies are a correlate of risk of COVID-19 in the CoVPN 3008 study in people with HIV

Using data from the CoVPN 3008 study, the authors show that the neutralizing antibody correlate of risk holds in people living with HIV. However, the nAb correlate was weaker and shorter-lived in a vaccine-immunity versus hybrid-immunity population.

Nonhlanhla N. Mkhize
Bo Zhang
Peter B. Gilbert
ResearchOpen Access06 Oct 2025
Nature Communications

Volume: 16, P: 1-19
Deep microbial colonization during impact-generated hydrothermal circulation at the Lappajärvi impact structure, Finland

Meteorite impacts can create long-lived hydrothermal systems that may spark onset of microbial life. At Finland’s Lappajärvi crater, minerals in fractures contain biosignatures of microbial life related to the hydrothermal circulation, offering clues to deep microbial colonization of Earth and beyond.

Jacob Gustafsson
Gordon R. Osinski
Henrik Drake
ResearchOpen Access17 Sept 2025
Nature Communications

Volume: 16, P: 1-14
Sensitive near point-of-care detection of asymptomatic and submicroscopic Plasmodium falciparum infections in African endemic countries

Limited diagnostic capacity for asymptomatic individuals hinders malaria elimination efforts in Africa. Here, the authors present a near point-of-care method based on colorimetric LAMP detection that outperforms expert microscopy and commercial rapid diagnostic tests for Plasmodium detection in asymptomatic and submicroscopic individuals.

Dimbintsoa Rakotomalala Robinson
Ivana Pennisi
Asadu Sserwanga
ResearchOpen Access10 Oct 2025
Nature Communications

Volume: 16, P: 1-13
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

Jon H. Condra
William A. Schleif
Emilio A. Emini
Research06 Apr 1995
Nature

Volume: 374, P: 569-571
Amygdala–liver signalling orchestrates glycaemic responses to stress

Studies in mice show that acute stress activates hyperglycaemia via activation of a medial amygdala–ventral hypothalamic circuit that controls glucose metabolic responses in the liver, independently of adrenal and pancreatic hormones.

J. R. E. Carty
K. Devarakonda
S. A. Stanley
ResearchOpen Access03 Sept 2025
Nature

P: 1-10
Stimulation of Synthesis of Ribonucleic Acid in Sub-apical Sections of Avena Coleoptile by Indolyl-3-acetic Acid

T. H. HAMILTON
R. J. MOORE
A. R. SCHRANK
Research18 Dec 1965
Nature

Volume: 208, P: 1180-1183
Bat Erosion as a Factor in Cave Formation

J. H. D. HOOPER
Research22 Nov 1958
Nature

Volume: 182, P: 1464
Neutralizing antibody correlate of protection against severe-critical COVID-19 in the ENSEMBLE single-dose Ad26.COV2.S vaccine efficacy trial

In this study, the authors report that post-vaccination neutralizing and binding antibody levels in the ENSEMBLE trial associate with Ad26.COV2.S vaccine efficacy (VE) against severe-critical COVID-19, with substantial VE even at unquantifiable neutralizing antibody titer.

Lindsay N. Carpp
Ollivier Hyrien
Griet A. Van Roey
ResearchOpen Access12 Nov 2024
Nature Communications

Volume: 15, P: 1-18
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Origin and evolutionary trajectories of brown algal sex chromosomes

Genomes of nine brown algal species with different sex determination systems show that U/V sex chromosomes evolved 450–224 Ma and show remarkable conservation of genes within the sex-determining region despite independent expansions of the sex locus in each lineage.

Josué Barrera-Redondo
Agnieszka P. Lipinska
Susana M. Coelho
ResearchOpen Access25 Aug 2025
Nature Ecology & Evolution

P: 1-18
Endogeneous Insulin and Growth Hormone Response in Children with Newly Diagnosed Diabetes Mellitus

A Drash
J B Field
A M Vazquez
Research01 Mar 1968
Pediatric Research

Volume: 2, P: 94-102
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases

Chronic inflammation, marked by C-reactive protein, has been associated with changes in methylation, but the causal relationship is unclear. Here, the authors perform a Epigenome-wide association meta-analysis for C-reactive protein levels and find that these methylation changes are likely the consequence of inflammation and could contribute to disease.

Matthias Wielscher
Pooja R. Mandaviya
Marjo-Riitta Järvelin
ResearchOpen Access03 May 2022
Nature Communications

Volume: 13, P: 1-14
Random Close Packing and the Heats of Fusion of Simple Liquids

J. L. FINNEY
J. D. BERNAL
Research01 Mar 1967
Nature

Volume: 213, P: 1079-1082
Diffusing protein binders to intrinsically disordered proteins

Using RFdiffusion, a general method for targeting intrinsically disordered proteins and regions for protein design has been developed.

Caixuan Liu
Kejia Wu
David Baker
ResearchOpen Access30 Jul 2025
Nature

Volume: 644, P: 809-817
Effect of the Cotton Plant in the Sudan Gezira on Certain Leaf-feeding Insect Pests

R. J. V. JOYCE
Research22 Nov 1958
Nature

Volume: 182, P: 1463-1464
Cocaine chemogenetics blunts drug-seeking by synthetic physiology

Cocaine chemogenetics in rats is a selective approach for countering drug reinforcement by clamping dopamine release in the presence of cocaine.

Juan L. Gomez
Christopher J. Magnus
Scott M. Sternson
ResearchOpen Access27 Aug 2025
Nature

P: 1-8
Reflexions on Mind

J. C. ECCLES
Books & Arts20 Jul 1973
Nature

Volume: 244, P: 183-184
Restoration of specific immunological virginity

I. McConnell
P. J. Lachmann
M. J. Hobart
Research12 Jul 1974
Nature

Volume: 250, P: 113-116
Metabolism of Ribonucleic Acid during the Oestrous Cycle

T. H. HAMILTON
C. C. WIDNELL
J. R. TATA
Research11 Mar 1967
Nature

Volume: 213, P: 992-995
Aliphatic Hydrocarbons in Pre-Cambrian Rocks

J. ORÓ
D. W. NOONER
Research01 Mar 1967
Nature

Volume: 213, P: 1082-1085
ATP, Activation, and the Heat of Shortening of Muscle

R. E. DAVIES
M. J. KUSHMERICK
R. E. LARSON
Research08 Apr 1967
Nature

Volume: 214, P: 148-151
Macrophages overcome mycoplasma infections of cells in vitro

L. Schimmelpfeng
U. Langenberg
J. Hinrich Peters
Research26 Jun 1980
Nature

Volume: 285, P: 661-662
Sex Differences in Immunologic Reponse: Studies of Antibody Production by Individual Spleen Cells after Stimulus with Escherichia coli Antigen

J F Kenny
J A Gray
Research01 Jun 1971
Pediatric Research

Volume: 5, P: 246-255
LUC7 proteins define two major classes of 5′ splice sites in animals and plants

Non-coding introns are excised from RNA transcripts of most eukaryotic genes by splicing. Here, Kenny et al. show that LUC7 proteins promote the splicing of different subsets of introns with distinct 5′ splice site sequences, and that these preferences are conserved from plants to human.

Connor J. Kenny
Michael P. McGurk
Christopher B. Burge
ResearchOpen Access20 Feb 2025
Nature Communications

Volume: 16, P: 1-15
Investigative needle core biopsies support multimodal deep-data generation in glioblastoma

Stereotactic needle biopsies are currently performed for diagnosis only in glioblastoma; this study highlights the depth of information available through multi-omics analysis.

Kenny K. H. Yu
Sreyashi Basu
Nathalie Y. R. Agar
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-23
Multiple conformations of ribosomal precursor RNA

J. M. W. SLACK
M-L. SARTIRANA
U. E. LOENING
Research24 Jan 1975
Nature

Volume: 253, P: 282-284
Chromosome Changes in Human Diploid-Cell Cultures Infected with Mycoplasma

G. R. PATON
J. P. JACOBS
F. T. PERKINS
Research03 Jul 1965
Nature

Volume: 207, P: 43-45
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma

Circular extrachromosomal DNA in high-risk medulloblastoma contributes to tumor heterogeneity and associates with relapse and survival. Enhancer rewiring events involving known oncogenes are frequent events, affecting transcription and proliferation.

Owen S. Chapman
Jens Luebeck
Lukas Chavez
ResearchOpen Access09 Nov 2023
Nature Genetics

Volume: 55, P: 2189-2199
Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics

Map belongs to a family of bacterial type III effectors that can regulate host cytoskeletal dynamics. Structural and biochemical data reveal that Map acts as a potent GEF for the GTPase Cdc42 and suggest how these effector molecules discriminate between target GTPases in their host.

Zhiwei Huang
Sarah E Sutton
Neal M Alto
Research20 Jul 2009
Nature Structural & Molecular Biology

Volume: 16, P: 853-860
A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies

MultiSTAAR provides a general and flexible statistical framework for functionally informed multi-trait rare variant analysis of biobank-scale sequencing studies by jointly analyzing multiple traits and incorporating annotation information.

Xihao Li
Han Chen
Xihong Lin
Research07 Feb 2025
Nature Computational Science

Volume: 5, P: 125-143
Teratogenic Activity of Nitrous Oxide

B. R. FINK
T. H. SHEPARD
R. J. BLANDAU
Research08 Apr 1967
Nature

Volume: 214, P: 146-148
Gender rating gap in online reviews

Across 1.2 billion data points, Bayerl et al. find that women submit higher online review ratings than men, which is probably due to their greater concern about social consequences when sharing negative feedback.

Andreas Bayerl
Yaniv Dover
Daniel Shapira
Research07 Oct 2024
Nature Human Behaviour

Volume: 9, P: 507-520
Elevated uric acid levels, mortality and cognitive impairment in children with severe malaria

In two independent cohorts of Ugandan children with severe malaria, elevated blood uric acid was found to be common and linked to both acute and postdischarge mortality, as well as poorer long-term cognitive outcomes.

Caitlin Bond
Olivia J. Bednarski
Andrea L. Conroy
Research24 Jan 2025
Nature Medicine

Volume: 31, P: 777-787
Hypoparathyroidism

Hypoparathyroidism is a disease characterized by inadequately low circulating levels of parathyroid hormone resulting in low calcium levels and increased phosphate levels in the blood. In this Primer, Mannstadt et al. summarize current knowledge of the prevalence, pathophysiology, clinical presentation and management of hypoparathyroidism.

Michael Mannstadt
John P. Bilezikian
Dolores M. Shoback
Reviews31 Aug 2017
Nature Reviews Disease Primers

Volume: 3, P: 1-21
Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Systematic analysis from the Global Burden of Disease study reported that, despite global improvements from 1990 to 2021, dietary iron deficiency-associated disease burden remains high in women, children and residents in low socio-demographic index countries.

Sooji Lee
Yejun Son
Nicholas. J. Kassebaum
Research22 Apr 2025
Nature Medicine

Volume: 31, P: 1809-1829
The Syndrome of Congenital Adrenocortical Unresponsiveness to ACTH. Report of Six Cases

Claude J Migeon
Frederic M Kenny
Robert M Blizzard
Research01 Nov 1968
Pediatric Research

Volume: 2, P: 501-513
FAM111A protects replication forks from protein obstacles via its trypsin-like domain

DNA-protein crosslinks represent obstacles on genomic DNA that can hamper progression of replication forks. Here, the authors reveal that FAM111A, a PCNA-interacting protein, plays part in mitigating the effect of protein obstacles on replication forks.

Yusuke Kojima
Yuka Machida
Yuichi J. Machida
ResearchOpen Access12 Mar 2020
Nature Communications

Volume: 11, P: 1-14
Action of Thyrocalcitonin on Bone

A. W. WASE
J. SOLEWSKI
J. SEIDENBERG
Research22 Apr 1967
Nature

Volume: 214, P: 388-389
Determination of Serum Luteinizing Hormone (SLH) by Radioimmunoassay in Disorders of Adolescent Sexual Development

Harvey J Guyda
Ann J Johanson
Robert M Blizzard
Research01 Nov 1969
Pediatric Research

Volume: 3, P: 538-544
Portable molecular diagnostic platform for rapid point-of-care detection of mpox and other diseases

The WHO’s designation of mpox as a public health emergency of international concern underscores the need for diagnostics to combat this escalating threat. Here, the authors present a portable POC molecular platform based on power-free DNA extraction and colourimetric LAMP.

Matthew L. Cavuto
Kenny Malpartida-Cardenas
Jesus Rodriguez-Manzano
ResearchOpen Access24 Mar 2025
Nature Communications

Volume: 16, P: 1-13
Molecular patterns and mechanisms of tumorigenesis in HPV-associated and HPV-independent sinonasal squamous cell carcinoma

Sinonasal squamous cell carcinoma (SNSCC) is an uncommon tumor, which has been associated with the human papillomavirus (HPV). Here the authors perform comprehensive genome-wide characterization of HPV-associated and HPV-independent SNSCC patient samples to reveal molecular patterns of tumorigenesis and identify HPV-driven mutational profiles.

Fernando T. Zamuner
Sreenivasulu Gunti
Nyall R. London Jr.
ResearchOpen Access11 Jun 2025
Nature Communications

Volume: 16, P: 1-13
Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts

David M. Lawson
Peter J. Artymiuk
Pauline M. Harrison
Research07 Feb 1991
Nature

Volume: 349, P: 541-544
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

Using data from a single time point, passenger-approximated clonal expansion rate (PACER) estimates the fitness of common driver mutations that lead to clonal haematopoiesis and identifies TCL1A activation as a mediator of clonal expansion.

Joshua S. Weinstock
Jayakrishnan Gopakumar
Siddhartha Jaiswal
Research12 Apr 2023
Nature

Volume: 616, P: 755-763
4′,6-Dichloroflavan (BW683C), a new anti-rhinovirus compound

D. J. Bauer
J. W. T. Selway
D. A. B. Young
Research23 Jul 1981
Nature

Volume: 292, P: 369-370
A paradox in the control of energy intake in the rat

NANCY J. ROTHWELL
M. J. STOCK
Research11 May 1978
Nature

Volume: 273, P: 146-147
Immune correlates analysis of mRNA-1345 RSV vaccine efficacy clinical trial

Identifying an immunologic marker as a correlate of protection (CoP) for RSV vaccination is important. Here, the authors demonstrate RSV neutralizing antibodies and RSV prefusion IgG binding antibodies as CoP for mRNA vaccination against RSV disease.

Chong Ma
Jiejun Du
Lingyi Zheng
ResearchOpen Access03 Jul 2025
Nature Communications

Volume: 16, P: 1-12
Thermal acclimation in temperate lizards

J. W. PATTERSON
P. M. C. DAVIES
Research19 Oct 1978
Nature

Volume: 275, P: 646-647
Tracing animal genomic evolution with the chromosomal-level assembly of the freshwater sponge Ephydatia muelleri

Reconstructing the early molecular evolution of animals requires genomic resources for non-bilaterian animals. Here, the authors present the chromosome-level genome of a freshwater sponge together with analyses of its genome architecture, methylation, developmental gene expression, and microbiome.

Nathan J. Kenny
Warren R. Francis
Sally P. Leys
ResearchOpen Access27 Jul 2020
Nature Communications

Volume: 11, P: 1-11
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk

Analyses of genome and exome sequencing data identify rare coding and structural variants associated with atrial fibrillation and highlight genetic links between atrial fibrillation and cardiomyopathies.

Seung Hoan Choi
Sean J. Jurgens
Patrick T. Ellinor
Research06 Mar 2025
Nature Genetics

Volume: 57, P: 548-562

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