The risk of pelvic nodal involvement in patients with high-risk prostate cancer has led to the development of whole-pelvis radiotherapy (WPRT); however, this approach remains controversial. In this Review, the authors discuss the mixed data surrounding WPRT and consider how advanced imaging techniques and ‘big data’ mining could improve patient selection and optimize WPRT by improving localization of subclinical disease.
- Hannah Tharmalingam
- Ananya Choudhury
- Peter J. Hoskin
