Breed et al. identify a subset of thymic SIRPα+ cDC2 dendritic cells that express CD301b, induced by type II cytokines, and high amounts of MHC-II. They find that the deletion of these cells can alter thymic CD4-single-positive repertoires, suggesting that they contribute to thymic tolerance.
- Elise R. Breed
- Matouš Vobořil
- Kristin A. Hogquist
