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Effect of energetic ions on edge-localized modes in tokamak plasmas

Edge-localized plasma modes in a tokamak can damage its innermost wall. Simulations now show that fast ions can modify the spatio-temporal structure of these modes. These effects need to be considered in the optimization of control techniques.

J. Dominguez-Palacios
S. Futatani
M. Zuin
ResearchOpen Access06 Jan 2025
Nature Physics

Volume: 21, P: 43-51
A control oriented strategy of disruption prediction to avoid the configuration collapse of tokamak reactors

Confining plasma and managing disruptions in tokamak devices is a challenge. Here the authors demonstrate a method predicting and possibly preventing disruptions and macroscopic instabilities in tokamak plasma using data from JET.

Andrea Murari
Riccardo Rossi
Michela Gelfusa
ResearchOpen Access18 Mar 2024
Nature Communications

Volume: 15, P: 1-19
Gram-scale synthesis of two-dimensional polymer crystals and their structure analysis by X-ray diffraction

Accessing synthetic two-dimensional polymers that are analogous to graphene is synthetically and analytically challenging. Now, single crystals of a simple-to-make monomer have been grown and then photopolymerized to form layered single crystals of covalently bonded two-dimensional polymer. Much like natural graphite, these crystals can be exfoliated to form thin sheets and single layers of the polymer.

Max J. Kory
Michael Wörle
A. Dieter Schlüter
Research27 Jul 2014
Nature Chemistry

Volume: 6, P: 779-784
Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form

Stephen Zewinger
Jochen Reiser
Thimoteus Speer
Research13 Feb 2023
Nature Immunology

Volume: 24, P: 412-413
Observation of magnetic islands in tokamak plasmas during the suppression of edge-localized modes

The suppression of edge-localized modes in tokamak plasmas is crucial to prevent them from damaging the walls of the chamber. Now experiments confirm the role that magnetic islands play in suppressing these detrimental modes.

Matthias Willensdorfer
Verena Mitterauer
S. Zoletnik
ResearchOpen Access28 Oct 2024
Nature Physics

Volume: 20, P: 1980-1988
A compendium of human gene functions derived from evolutionary modelling

Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.

Marc Feuermann
Huaiyu Mi
Paul D. Thomas
ResearchOpen Access26 Feb 2025
Nature

Volume: 640, P: 146-154
Costimulatory blockade by the induction of an endogenous xenospecific antibody response

Nicola J. Rogers
Vincenzo Mirenda
Robert I. Lechler
Research01 Aug 2000
Nature Immunology

Volume: 1, P: 163-168
Correction: Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb

Vincent Giguère
Estelita S. Ong
Clifford J. Tabin
Amendments and Corrections07 Sept 1989
Nature

Volume: 341, P: 80
Total Body Potassium Estimations in Young Children: The Interpretation of Results

M D Mann
M D Bowie
J D L Hansen
Research01 Nov 1974
Pediatric Research

Volume: 8, P: 879-884
Motor neurons generate pose-targeted movements via proprioceptive sculpting

Single motor neurons in Drosophila are stimulated to show that they direct head movements towards specific postures rather than generating fixed movement vectors, suggesting that the brain controls movements through a continuing proprioceptive–motor loop.

Benjamin Gorko
Igor Siwanowicz
Stephen J. Huston
Research20 Mar 2024
Nature

Volume: 628, P: 596-603
The Incorporation of n-3 and n-6 Essential Fatty Acids into the Chick Embryo from Egg Yolks Having Vastly Different Fatty Acid Compositions

Don S Lin
William E Connor
Gregory J Anderson
Research01 Jun 1991
Pediatric Research

Volume: 29, P: 601-605
Activity of nested neural circuits drives different courtship songs in Drosophila

Activation of nested, but not discrete, neural circuits drives alternative courtship songs in male Drosophila melanogaster, providing further insight into how the nervous system can drive the same motor systems to rapidly switch between different actions.

Hiroshi M. Shiozaki
Kaiyu Wang
David L. Stern
ResearchOpen Access28 Aug 2024
Nature Neuroscience

Volume: 27, P: 1954-1965
Reduced Erythrocyte Superoxide Dismutase Activity in Low Birth Weight Infants Given Iron Supplements

S M Barclay
P J Aggett
P Duffty
Research01 Mar 1991
Pediatric Research

Volume: 29, P: 297-301
New clues to environmental influences in glomerular disease

Research into genetic susceptibilities for proteinuric glomerular diseases has uncovered key pathogenic contributions from inheritable defects in podocytes. However, much less is known about environmental factors that may initiate or propagate podocyte injury. Seminal reports in 2011 provided new mechanistic insights into how this may occur.

Peter J. Nelson
Charles E. Alpers
News & Views13 Dec 2011
Nature Reviews Nephrology

Volume: 8, P: 65-66
Dr. R. C. Wallace

J. K. ROBERTSON
Comments & Opinion19 Mar 1955
Nature

Volume: 175, P: 493-494
Respiratory management in acute traumatic tetraplegia

D J E Cheshire
Research01 Feb 1964
Spinal Cord

Volume: 1, P: 252-261
Technetium-99m-MAG3 renal studies in spinal cord injury patients: normal range, reproducibility, and change as a function of duration and level of injury

W C Klingensmith III
D P Lammertse
J D Sutherland
Research01 Jun 1996
Spinal Cord

Volume: 34, P: 338-345
Corticosteroids, Thyrotropin-Releasing Hormone, and Antioxidant Enzymes in Preterm Lamb Lungs

Frans J Walther
Machiko Ikegami
Daniel H Polk
Research01 Dec 1991
Pediatric Research

Volume: 30, P: 518-521
Neuronal wiring diagram of an adult brain

FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to facilitate exploration and browsing.

Sven Dorkenwald
Arie Matsliah
Meet Zandawala
ResearchOpen Access02 Oct 2024
Nature

Volume: 634, P: 124-138
Environmental History

J. CHRISTOPHER JONES
Books & Arts19 Jul 1969
Nature

Volume: 223, P: 325-326
Esophagitis and esophageal motor abnormalities in patients with chronic spinal cord injuries

J G Stinneford
A Keshavarzian
M Durkin
Research01 Jun 1993
Spinal Cord

Volume: 31, P: 384-392
Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation

Overabundance of apolipoprotein C3 (ApoC3) is associated with atherosclerosis. Speer and colleagues demonstrate that ApoC3 activates the NLRP3 inflammasome via a non-canonical pathway contributing to inflammation and development of atherosclerosis.

Stephen Zewinger
Jochen Reiser
Thimoteus Speer
Research09 Dec 2019
Nature Immunology

Volume: 21, P: 30-41
Enhanced performance in fusion plasmas through turbulence suppression by megaelectronvolt ions

Experiments at the Joint European Torus tokamak show improved thermal ion confinement in the presence of highly energetic ions and Alfvénic instabilities in the plasma.

S. Mazzi
J. Garcia
I. Zychor
Research30 Jun 2022
Nature Physics

Volume: 18, P: 776-782
A tripartite complex of suPAR, APOL1 risk variants and α_vβ₃ integrin on podocytes mediates chronic kidney disease

A complex of suPAR and high-risk variants of APOL1 acting on integrin signaling in the kidney contributes to APOL1-associated chronic kidney disease.

Salim S Hayek
Kwi Hye Koh
Jochen Reiser
Research26 Jun 2017
Nature Medicine

Volume: 23, P: 945-953
Efficient generation of energetic ions in multi-ion plasmas by radio-frequency heating

Triggering and sustaining fusion reactions — with the goal of overall energy production — in a tokamak plasma requires efficient heating. Radio-frequency heating of a three-ion plasma is now experimentally shown to be a potentially viable technique.

Ye. O. Kazakov
J. Ongena
I. Zychor
Research19 Jun 2017
Nature Physics

Volume: 13, P: 973-978
The maillard or browning reaction in diabetes

W Garry John
Edmund J Lamb
Research01 Mar 1993
Eye

Volume: 7, P: 230-237
Lactate Genesis by Rat Liver and Muscle during Development

George J Dombrowski Jr.
Kenneth R Swiatek
Research01 Oct 1991
Pediatric Research

Volume: 30, P: 331-336
DOES EARLY DIETARY REGIMEN INFLUENCE CHOLESTEROL METABULISM IN ADULT LIFE? A STUDY IN MONGOLIAN GERBILS

A M Temmerman
R Vonk
J Fernandes
Research01 Aug 1987
Pediatric Research

Volume: 22, P: 237
Stretchable heterogeneous composites with extreme mechanical gradients

Heterogeneous composite materials, which are potentially useful for flexible electronics, are widespread in nature but synthetic examples are rare. Here, a site-specific hierarchical approach is used to fabricate composites with extreme local variations in elastic modulus and which are reversibly stretchable.

Rafael Libanori
Randall M. Erb
André R. Studart
Research11 Dec 2012
Nature Communications

Volume: 3, P: 1-9
Cross-linked telopeptides of type I and III collagens in malignant ovarian tumours in vivo

S Kauppila
M K Bode
J Risteli
ResearchOpen Access24 Sept 1999
British Journal of Cancer

Volume: 81, P: 654-661
[Book Reviews]

J. S. L. GILMOUR
Books & Arts12 Aug 1950
Nature

Volume: 166, P: 246
[Short Notices]

S. J. L.
Books & Arts14 Mar 1936
Nature

Volume: 137, P: 450-451
CDR3 loop flexibility contributes to the degeneracy of TCR recognition

Jean-Baptiste Reiser
Claudine Darnault
Bernard Malissen
Research03 Feb 2003
Nature Immunology

Volume: 4, P: 241-247
Low growth resilience to drought is related to future mortality risk in trees

Resilience to drought is crucial for tree survival under climate change. Here, DeSoto et al. show that trees that died during drought were less resilient to previous dry events compared to surviving conspecifics, but the resilience strategies differ between angiosperms and gymnosperms.

Lucía DeSoto
Maxime Cailleret
Jordi Martínez-Vilalta
ResearchOpen Access28 Jan 2020
Nature Communications

Volume: 11, P: 1-9
Transvascular delivery of small interfering RNA to the central nervous system

Attachment of a piece of viral protein to a small RNA achieves transfer of the RNA into neuronal cells in cell culture. This was also able to deliver an antiviral siRNA specifically into the brains of mice infected with encephalitis and achieve 80% protection. This study opens a new potential line of treatment for neuronal disease.

Priti Kumar
Haoquan Wu
N. Manjunath
Research17 Jun 2007
Nature

Volume: 448, P: 39-43
The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

Currently, there are few options for treating chronic kidney disease. The immunosuppressant cyclosporine A is effective, but the mechanism has been unclear. In this new report, the authors now show that the benefit of cyclosporine A is not through an effect on the immune system but rather through stabilizing the cytoskeleton, and thus the integrity, of a key cell type needed for proper kidney function.

Christian Faul
Mary Donnelly
Peter Mundel
Research24 Aug 2008
Nature Medicine

Volume: 14, P: 931-938
Manipulation of body fat composition with sterculic acid can inhibit mammary carcinomas in vivo

DE Khoo
B Fermor
NA Habib
Research01 Jan 1991
British Journal of Cancer

Volume: 63, P: 97-101
A visual motion detection circuit suggested by Drosophila connectomics

Reconstruction of a connectome within the fruitfly visual medulla, containing more than 300 neurons and over 8,000 chemical synapses, reveals a candidate motion detection circuit; such a circuit operates by combining displaced visual inputs, an operation consistent with correlation based motion detection.

Shin-ya Takemura
Arjun Bharioke
Dmitri B. Chklovskii
Research07 Aug 2013
Nature

Volume: 500, P: 175-181
Stochastic nonlinear dynamics of confined cell migration in two-state systems

Two-state micropatterns offer a unique platform to study cell migration. An equation of motion is inferred from a large ensemble of trajectories, revealing key differences in the nonlinear dynamics of healthy and cancerous cells.

David B. Brückner
Alexandra Fink
Chase P. Broedersz
Research04 Mar 2019
Nature Physics

Volume: 15, P: 595-601
In-vivo X-ray Dark-Field Chest Radiography of a Pig

Lukas B. Gromann
Fabio De Marco
Julia Herzen
ResearchOpen Access06 Jul 2017
Scientific Reports

Volume: 7, P: 1-7
A neural circuit for wind-guided olfactory navigation

Flies navigate to food sources by combining odour and wind-direction cues. This study identifies pathways to the fan-shaped body that encode these signals, and demonstrates how local neurons integrate odour- and wind information to guide navigation.

Andrew M. M. Matheson
Aaron J. Lanz
Katherine I. Nagel
ResearchOpen Access08 Aug 2022
Nature Communications

Volume: 13, P: 1-21
ISG-2: properties of the second International Simple Glass

Joseph V. Ryan
Nicholas J. Smith
Robert A. Schaut
ResearchOpen Access06 Jun 2023
npj Materials Degradation

Volume: 7, P: 1-9
High-performance calcium sensors for imaging activity in neuronal populations and microcompartments

The ‘jGCaMP7’ sensors are four genetically encoded calcium indicators with better sensitivity than state-of-the-art GCaMP6 and specifically improved for applications such as neuropil or wide-field imaging. The sensors are validated in vivo in both flies and mice.

Hod Dana
Yi Sun
Douglas S. Kim
Research17 Jun 2019
Nature Methods

Volume: 16, P: 649-657
How many drug targets are there?

For the past decade, the number of molecular targets for approved drugs has been debated. In this article and the accompanying poster, Overington and colleagues provide a comprehensive survey of current drug targets and a wealth of associated information on the characteristics of target families and the drugs that modulate them.

John P. Overington
Bissan Al-Lazikani
Andrew L. Hopkins
Reviews01 Dec 2006
Nature Reviews Drug Discovery

Volume: 5, P: 993-996
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

Kerry J. Ressler
Kristina B. Mercer
Victor May
Research23 Feb 2011
Nature

Volume: 470, P: 492-497
Using at least 5×10⁶/kg CD34⁺ cells for autologous stem cell transplantation significantly reduces febrile complications and use of antibiotics after transplantation

C Scheid
A Draube
D Söhngen
Research15 Jun 1999
Bone Marrow Transplantation

Volume: 23, P: 1177-1181
The immunological synapse and CD28-CD80 interactions

Shannon K. Bromley
Andrea Iaboni
Michael L. Dustin
Research19 Nov 2001
Nature Immunology

Volume: 2, P: 1159-1166
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease

Soluble uPAR is known to contribute to certain types of chronic kidney disease, and myeloid cells from the bone marrow have now been shown to be a key source of this factor.

Eunsil Hahm
Changli Wei
Jochen Reiser
Research12 Dec 2016
Nature Medicine

Volume: 23, P: 100-106
Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1

Focal and segmental glomerulosclerosis, or renal scarring, is a debilitating disease. The identification of the molecular mechanisms of its initiation and progression has been limited, thus hampering the development of proper animal models. Dontscho Kerjaschki and his colleagues now report that microRNA-193a is elevated in human cases of the disease and that transgenic expression in mice is sufficient to cause the condition.

Christoph A Gebeshuber
Christoph Kornauth
Dontscho Kerjaschki
Research17 Mar 2013
Nature Medicine

Volume: 19, P: 481-487
Anatomy and pathology of the vitreo-retinal interface

J Sebag
Research01 Nov 1992
Eye

Volume: 6, P: 541-552

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