Nature Search

Rebels of art and science: the empirical drive of the Pre-Raphaelites

John Holmes explores how the Victorian art movement enshrined the findings of a fecund age.

John Holmes
Books & Arts24 Oct 2018
Nature

Volume: 562, P: 490-491
On the Eocene Flora of Bournemouth

J. STARKIE GARDNER
News25 Dec 1879
Nature

Volume: 21, P: 181-183
How diabetes went to our heads

A spate of recent studies has identified key neural pathways that control glucose production from the liver. They may provide a new link between obesity and type 2 diabetes.

Randy J Seeley
Matthias Tschöp
News & Views01 Jan 2006
Nature Medicine

Volume: 12, P: 47-49
Biosynthesis of cadmium sulphide quantum semiconductor crystallites

C. T. Dameron
R. N. Reese
D. R. Winge
Research13 Apr 1989
Nature

Volume: 338, P: 596-597
Novel mutations in the duplicated region of PKD1 gene

R Perrichot
B Mercier
C Ferec
Research15 Jun 2000
European Journal of Human Genetics

Volume: 8, P: 353-359
Dopamine D₂ Receptor Availability in Opiate-Dependent Subjects before and after Naloxone-Precipitated Withdrawal

Gene-Jack Wang
Nora D Volkow
Kathy Pascani
Research01 Feb 1997
Neuropsychopharmacology

Volume: 16, P: 174-182
Automatic avoidance of obstacles is a dorsal stream function: evidence from optic ataxia

Igor Schindler
Nichola J Rice
A David Milner
Research20 Jun 2004
Nature Neuroscience

Volume: 7, P: 779-784
Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production

Hypothalamic melanocortin neurons regulate systemic glucose homeostasis through incompletely understood pathways. Here, the authors show that a subset of pro-opiomelanocortin neurons innervate the liver via preganglionic parasympathetic cholinergic neurons in the dorsal motor nucleus of the vagus and that stimulation of this pathway elevates blood glucose levels

Eunjin Kwon
Hye-Young Joung
Young-Hwan Jo
ResearchOpen Access08 Dec 2020
Nature Communications

Volume: 11, P: 1-13
Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat

Joakim Galli
Luo-Sheng Li
Holger Luthman
Research01 Jan 1996
Nature Genetics

Volume: 12, P: 31-37
British Earthworms

FRANK J. COLE
Research26 Jan 1893
Nature

Volume: 47, P: 295
Striatal dopamine nerve terminal markers in human, chronic methamphetamine users

Julie M. Wilson
Kathryn S. Kalasinsky
Stephen J. Kish
Research01 Jun 1996
Nature Medicine

Volume: 2, P: 699-703
Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing

Information on immune receptor repertoire provides important insights on disease progression and therapy development, but can be expensive and time-consuming to obtain. Here the authors report ImReP, a computational method that can extract detailed immune repertoire information from existing tissue-specific RNA sequencing data.

Igor Mandric
Jeremy Rotman
Serghei Mangul
ResearchOpen Access19 Jun 2020
Nature Communications

Volume: 11, P: 1-14
A simple way to make tough ceramics

W. J. Clegg
K. Kendall
J. D. Birchall
Research04 Oct 1990
Nature

Volume: 347, P: 455-457
Synthesis of inorganic nanophase materials in supramolecular protein cages

Fiona C. Meldrum
Vanessa J. Wade
Stephen Mann
Research21 Feb 1991
Nature

Volume: 349, P: 684-687
Shock-induced martensitic phase transformation of oriented graphite to diamond

D. J. Erskine
W. J. Nellis
Research24 Jan 1991
Nature

Volume: 349, P: 317-319
Quantization effects in the photoelectrochemistry of superlattice photoelectrodes

A. J. Nozik
B. R. Thacker
J. M. Olson
Research04 Jul 1985
Nature

Volume: 316, P: 51-53
Clonally expanded EOMES⁺ Tr1-like cells in primary and metastatic tumors are associated with disease progression

Human primary and metastatic tumors harbor CD4⁺ T_reg cells that can suppress antitumor immune responses. Bonnal et al. identify an intratumoral type 1 T_reg-like CD4⁺ T cell subset that expresses the transcription factor EOMES, granzyme K and CHI3L2. This EOMES⁺ T cell subset correlates with disease progression but is responsive to PD-1 checkpoint blockade immunotherapy.

Raoul J. P. Bonnal
Grazisa Rossetti
Massimiliano Pagani
Research20 May 2021
Nature Immunology

Volume: 22, P: 735-745
Global diversity and distribution of antibiotic resistance genes in human wastewater treatment systems

Wastewater treatment plants are important reservoirs of antibiotic resistance genes (ARGs). Here, the authors analyze ARGs in a global collection of samples from wastewater treatment plants across six continents, providing insights into biotic and abiotic mechanisms that appear to control ARG diversity and distribution.

Congmin Zhu
Linwei Wu
Jizhong Zhou
ResearchOpen Access29 Apr 2025
Nature Communications

Volume: 16, P: 1-14
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

Tony K T Lam
Alessandro Pocai
Luciano Rossetti
Research27 Feb 2005
Nature Medicine

Volume: 11, P: 320-327
Solid-state perspectives of the photoelectrochemistry of semiconductor–electrolyte junctions

F. Williams
A. J. Nozik
Reviews01 Nov 1984
Nature

Volume: 312, P: 21-27
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Land-Reclamation in Italy

E. J. RUSSELL
Books & Arts04 Jul 1936
Nature

Volume: 138, P: 4-6
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

FXR regulates the levels of ACE2 in tissues of the respiratory and gastrointestinal systems that are affected by COVID-19, and inhibiting FXR with ursodeoxycholic acid downregulates ACE2 and reduces susceptibility to SARS-CoV-2 infection.

Teresa Brevini
Mailis Maes
Fotios Sampaziotis
ResearchOpen Access05 Dec 2022
Nature

Volume: 615, P: 134-142
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Computationally designed hyperactive Cas9 enzymes

The ability to alter the genomes of living cells is key to understanding how genes influence the functions of organisms and will be critical to modify living systems for useful purposes. Here, the authors use computational design to discover Cas9 enzymes with increased activity.

Pascal D. Vos
Giulia Rossetti
Oliver Rackham
ResearchOpen Access31 May 2022
Nature Communications

Volume: 13, P: 1-11
Optic ataxia errors depend on remapped, not viewed, target location

A Z Khan
L Pisella
Y Rossetti
Research13 Mar 2005
Nature Neuroscience

Volume: 8, P: 418-420
Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins

Tony K T Lam
Roger Gutierrez-Juarez
Luciano Rossetti
Research04 Feb 2007
Nature Medicine

Volume: 13, P: 171-180
On-demand male contraception via acute inhibition of soluble adenylyl cyclase

Half of all pregnancies are unintended; thus, existing family planning options are inadequate. This proof-of-concept study validates an on-demand contraception strategy for men, showing high effectiveness in quickly and temporarily reducing male fertility in mice.

Melanie Balbach
Thomas Rossetti
Lonny R. Levin
ResearchOpen Access14 Feb 2023
Nature Communications

Volume: 14, P: 1-12
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Dopamine transporters increase in human brain after alcohol withdrawal

T P J Laine
A Ahonen
M Hillbom
Research17 Mar 1999
Molecular Psychiatry

Volume: 4, P: 189-191
Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

Ellen B. Katz
Antine E. Stenbit
Maureen J. Charron
Research14 Sept 1995
Nature

Volume: 377, P: 151-155
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

Neurological disorders such as temporal lobe epilepsy (TLE) are known to be regulated by gene networks. In this study, the authors describe a genome-wide approach that uses samples of hippocampal tissue from patients with TLE, to identify the gene Sestrin 3 (SESN3) as a positive regulator of the disease.

Michael R. Johnson
Jacques Behmoaras
Enrico Petretto
Research23 Jan 2015
Nature Communications

Volume: 6, P: 1-11
Erratum: Automatic avoidance of obstacles is a dorsal stream function: evidence from optic ataxia

Igor Schindler
Nichola J Rice
A David Milner
Amendments and Corrections01 Sept 2004
Nature Neuroscience

Volume: 7, P: 1011
Measurement of the inelastic proton–proton cross-section at √s=7 TeV with the ATLAS detector

The measurement of the total cross-section of proton–proton collisions is of fundamental importance for particle physics. Here, the first measurement of the inelastic cross-section is presented for proton–proton collisions at an energy of 7 teraelectronvolts using the ATLAS detector at the Large Hadron Collider.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access06 Sept 2011
Nature Communications

Volume: 2, P: 1-14
Evidence for light-by-light scattering in heavy-ion collisions with the ATLAS detector at the LHC

Quantum electrodynamics predicts a rare process in which light is scattered by light. The ATLAS Collaboration reports signs of this elusive effect in the collisions of ultra-relativistic lead ions.

M. Aaboud
G. Aad
L. Zwalinski
ResearchOpen Access14 Aug 2017
Nature Physics

Volume: 13, P: 852-858
The microstructure and micromechanics of the tendon–bone insertion

High-resolution imaging, composition analysis and mechanical testing provide a new insight into the structure and function of the Achilles enthesis.

L. Rossetti
L. A. Kuntz
A. R. Bausch
Research27 Feb 2017
Nature Materials

Volume: 16, P: 664-670
The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

Christopher J. Ward
Marie C. Hogan
Peter C. Harris
Research04 Feb 2002
Nature Genetics

Volume: 30, P: 259-269
The ‘carnivore connection’—evolutionary aspects of insulin resistance

S Colagiuri
J Brand Miller
Research18 Mar 2002
European Journal of Clinical Nutrition

Volume: 56, P: S30-S35
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

Germline mutations in BRCA1 or BRCA2 tumour suppressor genes predispose to different cancers, as does oncogene activation. Here the authors reveal that aberrant transcription of specific genes triggered by activation of the oncogene β-catenin causes replication failure and cell death in the context of BRCA1/2 deficiency.

Rebecca A. Dagg
Gijs Zonderland
Madalena Tarsounas
ResearchOpen Access13 Aug 2021
Nature Communications

Volume: 12, P: 1-17
Toxic Effects of Groundnut Meal Containing Aflatoxin to Rats and Guinea-Pigs

W H Butler
J M Barnes
Research01 Dec 1963
British Journal of Cancer

Volume: 17, P: 699-710
Extracorporeal photopheresis (ECP) in the treatment of chronic graft-versus-host disease (GVHD)

FJ Child
R Ratnavel
R Russell-Jones
Research07 May 1999
Bone Marrow Transplantation

Volume: 23, P: 881-887
Actin cables and comet tails organize mitochondrial networks in mitosis

During mitosis, complementary actin-based mechanisms ensure equal and random distributions of mitochondria among daughter cells following symmetrical cell division.

Andrew S. Moore
Stephen M. Coscia
Erika L. F. Holzbaur
Research03 Mar 2021
Nature

Volume: 591, P: 659-664
Hypothalamic K_ATP channels control hepatic glucose production

Alessandro Pocai
Tony K. T. Lam
Luciano Rossetti
Research21 Apr 2005
Nature

Volume: 434, P: 1026-1031
Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

Impairment of cognitive function is a common feature of many neurodevelopmental disorders. Systems genetics analysis in the brain uncovered a convergent gene network for both cognition and neurodevelopmental disorders. As the network does not recapitulate known pathways, this finding represents a new basis for understanding factors influencing normal and disordered cognition.

Michael R Johnson
Kirill Shkura
Enrico Petretto
Research21 Dec 2015
Nature Neuroscience

Volume: 19, P: 223-232
Global diversity and biogeography of bacterial communities in wastewater treatment plants

Global sampling of microbial communities associated with wastewater treatment plants and application of ecological theory revealed a small, core bacterial community associated with performance and provides insights into the community dynamics in this environment.

Linwei Wu
Daliang Ning
Jizhong Zhou
Research13 May 2019
Nature Microbiology

Volume: 4, P: 1183-1195
Author Correction: Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing

Igor Mandric
Jeremy Rotman
Serghei Mangul
Amendments and CorrectionsOpen Access04 Sept 2020
Nature Communications

Volume: 11, P: 1
Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms

Christoph Buettner
Evan D Muse
Luciano Rossetti
Research01 Jun 2008
Nature Medicine

Volume: 14, P: 667-675
A new piece in the diabetes puzzle

Increased levels of circulating triglyceride and free fatty acids are common features of diabetic dyslipidemia. Positional cloning has led to the identification of a liver-derived protein, angiopoietin-like protein 3, that is largely responsible for diabetic dyslipidemia in an animal model of type 2 diabetes mellitus.

Luciano Rossetti
Ira J. Goldberg
News & Views01 Feb 2002
Nature Medicine

Volume: 8, P: 112-114
Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4⁺ T cells by the microRNA miR-125b

MicroRNAs are post-transcriptional regulators of gene expression. Pagani and colleagues identify specific microRNA signatures and their target genes in various human lymphoid subsets.

Riccardo L Rossi
Grazisa Rossetti
Massimiliano Pagani
Research26 Jun 2011
Nature Immunology

Volume: 12, P: 796-803
A first update on mapping the human genetic architecture of COVID-19

Gita A. Pathak
Juha Karjalainen
J. Kenneth Baillie
ResearchOpen Access03 Aug 2022
Nature

Volume: 608, P: E1-E10

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