Nature Search

Naturally occurring viral R plasmid with a circular supercoiled genome in the extracellular state

J. M. PEMBERTON
W. T. TUCKER
Research01 Mar 1977
Nature

Volume: 266, P: 50-51
ES cells for troubled hearts

Cardiomyocytes derived from human embryonic stem cells prove beneficial in an animal model of myocardial infarction.

Michael Rubart
Loren J Field
News & Views01 Sept 2007
Nature Biotechnology

Volume: 25, P: 993-994
Reported Occurrence of European Fishes on the Tavoy Coast, Burma

J. R. NORMAN
Research22 Feb 1936
Nature

Volume: 137, P: 321
Fossil Pollen in Scottish Tertiary Coals

J. B. SIMPSON
Research22 Feb 1936
Nature

Volume: 137, P: 321
Recent Research on Cancer

J. P. LOCKHART-MUMMERY
Research22 Feb 1936
Nature

Volume: 137, P: 321
Critical Mass Measurements for the Merlin Research Reactor

D. R. CHICK
K. FIRTH
A. J. SALMON
Research26 Apr 1958
Nature

Volume: 181, P: 1171-1173
Oscillations in Magnetrons

J. S. MCPETRIE
Research22 Feb 1936
Nature

Volume: 137, P: 321-322
Skatole as a Growth-Promoting Substance

J. GLOVER
Research22 Feb 1936
Nature

Volume: 137, P: 320-321
Seeing red in Queensland

N. D. J. COOK
I. DAVIDSON
S. SUTTON
Research30 Nov 1989
Nature

Volume: 342, P: 487
Is the viceroy a batesian mimic?

CYRIL A. CLARKE
F. M. M. CLARKE
NEVILLE A. MARSH
Research20 Jun 1991
Nature

Volume: 351, P: 612
Tau-targeting antisense oligonucleotide MAPT_Rx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

Evaluation of a tau-targeting antisense oligonucleotide in a phase 1 trial of patients with mild AD found it was well tolerated and resulted in a sustained reduction of tau protein levels.

Catherine J. Mummery
Anne Börjesson-Hanson
Roger M. Lane
ResearchOpen Access24 Apr 2023
Nature Medicine

Volume: 29, P: 1437-1447
Thermal Neutron Distribution in a Slab of Paraffin

B. S. SMITH
J. H. TAIT
Research04 Feb 1950
Nature

Volume: 165, P: 196
[Obituaries]

J. S. MACDONALD
Comments & Opinion25 Sept 1926
Nature

Volume: 118, P: 453-454
Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform

Investigations of human cardiac disease involving human pluripotent stem cell-derived cardiomyocytes are limited by the disorganized presentation of biomechanical cues resulting in cell immaturity. Here the authors develop a platform of micron-scale 2D cardiac muscle bundles to precisely deliver physiologic cues, improving reproducibility and throughput.

Yao-Chang Tsan
Samuel J. DePalma
Adam S. Helms
ResearchOpen Access25 Oct 2021
Nature Communications

Volume: 12, P: 1-16
Steam Power and Mill Work

N. J. L.
Books & Arts04 Jul 1895
Nature

Volume: 52, P: 218-219
Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

W. H. Moolenaar
L. G. J. Tertoolen
S. W. de Laat
Research22 Nov 1984
Nature

Volume: 312, P: 371-374
FGF4 dissociates anti-tumorigenic from differentiation signals of retinoic acid in human embryonal carcinomas

Wolfgang J Maerz
Jose Baselga
Ethan Dmitrovsky
Research14 Aug 1998
Oncogene

Volume: 17, P: 761-767
Stepwise enzymatic dephosphorylation of inositol 1,4,5-trisphosphate to inositol in liver

Diane J. Storey
Stephen B. Shears
Robert H. Michell
Research22 Nov 1984
Nature

Volume: 312, P: 374-376
Deletion of self-reactive thymocytes occurs at a CD4⁺8⁺ precursor stage

B. J. Fowlkes
R. H. Schwartz
D. M. Pardoll
Research18 Aug 1988
Nature

Volume: 334, P: 620-623
Tumours and viruses in mice injected with plutonium

J. F. LOUTIT
E. L. LLOYD
Research24 Mar 1977
Nature

Volume: 266, P: 355-357
The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

Jeffery A. Porter
Doris P. von Kessler
Philip A. Beachy
Research23 Mar 1995
Nature

Volume: 374, P: 363-366
Human growth-differentiation factor 3 (hGDF3): developmental regulation in human teratocarcinoma cell lines and expression in primary testicular germ cell tumours

Andrea AD Caricasole
Ron HN van Schaik
Adriana JM van den Eijnden-van Raaij
Research21 Jan 1998
Oncogene

Volume: 16, P: 95-103
Pigmentation of the ladybird beetle Coccinella septempunctata by carotenoids not of plant origin

GEORGE BRITTON
WILLIAM J. S. LOCKLEY
TREVOR W. GOODWIN
Research01 Mar 1977
Nature

Volume: 266, P: 49-50
Protein kinase C mediates neural induction in Xenopus laevis

A. P. Otte
C. H. Koster
A. J. Durston
Research18 Aug 1988
Nature

Volume: 334, P: 618-620
Cloning human embryos

Human embryonic stem cells have at last been generated by a technique called somatic-cell nuclear transfer. Further research on such cells should provide insight into ways of improving the generation of stem cells by reprogramming.

Christine L. Mummery
Bernard A. J. Roelen
News & Views12 Jun 2013
Nature

Volume: 498, P: 174-175
Quasi-periodic X-ray eruptions years after a nearby tidal disruption event

The detection and modelling of nine X-ray quasi-periodic eruptions from a nearby tidal disruption event shows that these eruptions arise in accretion disks around massive black holes, left behind by tidally disrupted stars, and that an orbiting body colliding with this disk is a plausible explanation for the X-ray variability.

M. Nicholl
D. R. Pasham
D. R. Young
ResearchOpen Access09 Oct 2024
Nature

Volume: 634, P: 804-808
Voices of biotech

Nature Biotechnology asks a selection of researchers about the most exciting frontier in their field and the most needed technologies for advancing knowledge and applications.

Ido Amit
David Baker
Tian Zhang
Special Features10 Mar 2016
Nature Biotechnology

Volume: 34, P: 270-275
Author Correction: Tau-targeting antisense oligonucleotide MAPT_Rx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

Catherine J. Mummery
Anne Börjesson-Hanson
Roger M. Lane
Amendments and CorrectionsOpen Access16 Oct 2023
Nature Medicine

Volume: 30, P: 304
A trial of nonspecific immunotherapy using systemic C. parvum in treated patients with Dukes B and C colorectal cancer

R G Souter
P G Gill
P J Morris
Research01 Apr 1982
British Journal of Cancer

Volume: 45, P: 506-512
Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia

Individuals with the disease hereditary hemorrhagic telangiectasia have vascular defects that lead to frequent hemorrhages. Franck Lebrin et al. now show that thalidomide, tested as a therapy in a small set of individuals with this disease, lowers the frequency of hemorrhaging and the need for blood transfusions. The authors tie the antihemorrhagic effects of thalidomide to its ability to promote blood vessel maturation through effects on PDGF-B expression by endothelial cells and on pericyte cell proliferation (pages 370–372).

Franck Lebrin
Samly Srun
Christine L Mummery
Research04 Apr 2010
Nature Medicine

Volume: 16, P: 420-428
Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

Cardiomyocytes obtained from human induced pluripotent stem cells are increasingly used for drug testing, but they are not always predictive of the heart contractile responses. Here the authors develop a method to measure cytosolic calcium, action potentials and contraction simultaneously, to achieve higher sensitivity for drug screenings.

Berend J. van Meer
Ana Krotenberg
Christine L. Mummery
ResearchOpen Access20 Sept 2019
Nature Communications

Volume: 10, P: 1-9
Bilirubin Toxicity in a Neuroblastoma Cell Line N-115:1. Effects on Na+K+ ATPase, [3H]- Thymidine Uptake, L-[35S]-Methionine Incorporation, and Mitochondrial Function

Y Amit
G Chan
D Schiff
Research01 Apr 1989
Pediatric Research

Volume: 25, P: 364-368
Abnormal Signal Transduction in a Patient with Severe Combined Immunodeficiency Disease

Ger T Rijkers
John G M Scharenberg
Ben J M Zegers
Research01 Mar 1991
Pediatric Research

Volume: 29, P: 306-309
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease

Results from the phase 2/3 clinical trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease reveal no beneficial effects on cognitive measures despite a significant reduction in amyloid plaques and other key biomarkers in those treated with gantenerumab.

Stephen Salloway
Martin Farlow
Christopher H. van Dyck
Research21 Jun 2021
Nature Medicine

Volume: 27, P: 1187-1196
Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi

Knoblich and colleagues use a library of Drosophila strains expressing inducible hairpin RNA interference constructs to study the Notch signalling pathway during external sensory organ development. They assign putative loss-of-function phenotypes to 21.2% of the protein-coding Drosophila genes, identify 6 new genes involved in asymmetric cell division and 23 novel genes regulating the Notch signalling pathway.

Jennifer L. Mummery-Widmer
Masakazu Yamazaki
Juergen A. Knoblich
Research12 Apr 2009
Nature

Volume: 458, P: 987-992
Author Correction: Casimir spring and dilution in macroscopic cavity optomechanics

J. Mummery
J. M. Pate
M. E. Tobar
Amendments and Corrections01 Dec 2021
Nature Physics

Volume: 18, P: 118-119
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Parapsychology

E. J. FARGE
Correspondence01 Oct 1968
Nature

Volume: 220, P: 412
Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells

The development of human cardiovascular progenitor cells provides a renewable source of cardiac cell types.

Matthew J Birket
Marcelo C Ribeiro
Christine L Mummery
Research01 Sept 2015
Nature Biotechnology

Volume: 33, P: 970-979
All-trans-retinoic acid metabolites significantly inhibit the proliferation of MCF-7 human breast cancer cells in vitro

J Van heusden
W Wouters
G Smets
Research01 Jan 1998
British Journal of Cancer

Volume: 77, P: 26-32
Prof. Archibald Young

J. R. LEARMONTH
Comments & Opinion02 Sept 1939
Nature

Volume: 144, P: 407-408
The two “hit” and multiple “hit” theories of carcinogenesis.

D J Ashley
Research01 Jun 1969
British Journal of Cancer

Volume: 23, P: 313-328
The Teeth and Civilisation

J. HOWARD MUMMERY
Research07 Jun 1894
Nature

Volume: 50, P: 123-124
Capt. G. T. McCaw, C. M. G., O. B. E

J. CLENDINNING
Comments & Opinion05 Dec 1942
Nature

Volume: 150, P: 656
Prof. Heinrich Kayser, For.Mem.R.S

F. J. M. STRATTON
Comments & Opinion31 May 1947
Nature

Volume: 159, P: 732
Chemical and Biological Action of Radiations

J. WEISS
Books & Arts25 Aug 1956
Nature

Volume: 178, P: 388-389
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-18
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid

Perivascular and leptomeningeal macrophages, collectively termed here parenchymal border macrophages, are shown to regulate flow dynamics of cerebrospinal fluid, implicating this cell population as new therapeutic targets in neurological diseases such as Alzheimer’s.

Antoine Drieu
Siling Du
Jonathan Kipnis
Research09 Nov 2022
Nature

Volume: 611, P: 585-593
An acute immune response underlies the benefit of cardiac stem cell therapy

Cardiac stem cell therapy in mouse models of ischaemia–reperfusion injury demonstrates that improvement in heart function is linked to an immune response characterized by the induction of CCR2⁺ and CX3CR1⁺ macrophages.

Ronald J. Vagnozzi
Marjorie Maillet
Jeffery D. Molkentin
Research27 Nov 2019
Nature

Volume: 577, P: 405-409
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

A gene regulatory network, including the transcription factor Nkx2-5, regulates cardiac development. Here, the authors show that on deletion of NKX2-5 from human embryonic stem cells, there is impaired cardiomyogenesis and changes in action potentials, and that this is regulated via HEY2.

David J. Anderson
David I. Kaplan
David A. Elliott
ResearchOpen Access10 Apr 2018
Nature Communications

Volume: 9, P: 1-13

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