Nature Search

Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction

Differentiation into cytotoxic lymphocytes requires T-cell instruction by appropriately activated dendritic cells (DCs). Here the authors show that two DC lineages in the lung are selectively activated by either Toll-like receptor 3 or 7 to induce cytotoxic T-cell function.

A Nicole Desch
Sophie L. Gibbings
Claudia Jakubzick
Research19 Aug 2014
Nature Communications

Volume: 5, P: 1-12
Dry late accretion inferred from Venus’s coupled atmosphere and internal evolution

Venus’s atmospheric composition suggests limited water delivery to the terrestrial planets by late accretion, according to numerical simulations of the interior and atmospheric evolution of Venus under various late accretion scenarios.

C. Gillmann
G. J. Golabek
V. Debaille
Research07 Apr 2020
Nature Geoscience

Volume: 13, P: 265-269
Genetic Background of Circadian Rhythms

R. BARCAL
J. SOVA
J. MATOUSEK
Research14 Dec 1968
Nature

Volume: 220, P: 1128-1131
Intensive measurements of turbulence and shear in the equatorial undercurrent

M. C. Gregg
H. Peters
T. J. Shay
Research14 Nov 1985
Nature

Volume: 318, P: 140-144
Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer

Dendritic cells (DC) present tumour antigens to T cells but this process is defective in the tumour microenvironment. Here the authors find that downregulation of cholesterol 25-hydroxylase underlies defective cross presentation of tumour antigens.

Zhen Lu
Jinyun Chen
Serge Y. Fuchs
ResearchOpen Access04 Nov 2022
Nature Communications

Volume: 13, P: 1-17
Accurate radiometers should measure the output of the Sun

T. J. Quinn
C. Fröhlich
Correspondence28 Oct 1999
Nature

Volume: 401, P: 841
Isotopic evolution of planetary crusts by hypervelocity impacts evidenced by Fe in microtektites

Fe isotopic composition of the distal ejecta of a terrestrial impact crater records both evaporation and condensation, refining the nature of the isotopic fractionation taking place during hypervelocity impacts in the Solar System.

S. M. Chernonozhkin
C. González de Vega
S. Goderis
ResearchOpen Access22 Sept 2021
Nature Communications

Volume: 12, P: 1-12
A steeply-inclined trajectory for the Chicxulub impact

The authors here present a 3D model that simulates the formation of the Chicxulub impact crater. Based on asymmetries in the subsurface structure of the Chicxulub crater, the authors diagnose impact angle and direction and suggest a steeply inclined (60° to horizontal) impact from the northeast.

G. S. Collins
N. Patel
T. J. Bralower
ResearchOpen Access26 May 2020
Nature Communications

Volume: 11, P: 1-10
Self-assembled lipid–prodrug nanoparticles

Combining the benefits of nanoparticle carriers and prodrugs can improve drug delivery efficiency. This Review discusses the design of lipid–prodrug nanomedicines with self-assembly properties for modulating drug release, reducing drug metabolism, and improving the pharmacokinetics and biodistribution for the treatment of severe diseases.

Patrick Couvreur
Sinda Lepetre-Mouelhi
Maria J. Blanco-Prieto
Reviews28 Jun 2023
Nature Reviews Bioengineering

Volume: 1, P: 749-768
1599 IDENTIFICATION OF INTERMEDIATE FILAMENT AGGREGATES IN CULTURED SKIN FIBROBLASTS FROM PATIENTS WITH GIANT AXONAL NEUROPATHY

Sergio D J Pena
Charles R Scriver
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 709
Nutrition of the Very Young

J. DAVIDSON
News09 Nov 1957
Nature

Volume: 180, P: 949-950
149 MITOCHONDRIAL MYOPATHY: DEFICIENCY OF HEAT SHOCK PROTEIN 60 (HSP60)

E Agsteribbe
O H Skjeldal
R S Gupta
Research01 Dec 1991
Pediatric Research

Volume: 30, P: 653
Generation of CD4⁺ and CD8⁺ T–cell clones from PBLs of HIV–1 infected subjects using herpesvirus saimiri

Kunal Saha
Pavel Sova
David J. Volsky
Advertorial01 Nov 1996
Nature Medicine

Volume: 2, P: 1272-1275
Cytokine-armed vaccinia virus infects the mesothelioma tumor microenvironment to overcome immune tolerance and mediate tumor resolution

C Jackaman
D J Nelson
Research12 Feb 2010
Cancer Gene Therapy

Volume: 17, P: 429-440
SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2′deoxycytidine to increase SPARC expression and improve therapy response

S Cheetham
M J Tang
I T Tai
ResearchOpen Access06 May 2008
British Journal of Cancer

Volume: 98, P: 1810-1819
A comprehensive collection of systems biology data characterizing the host response to viral infection

Brian D. Aevermann
Brett E. Pickett
Richard H. Scheuermann
ResearchOpen Access14 Oct 2014
Scientific Data

Volume: 1, P: 1-21
Armed replicating adenoviruses for cancer virotherapy

J J Cody
J T Douglas
Reviews06 Feb 2009
Cancer Gene Therapy

Volume: 16, P: 473-488
Evaluation of adenovirus vectors containing serotype 35 fibers for tumor targeting

S Ni
A Gaggar
A Lieber
Research28 Jul 2006
Cancer Gene Therapy

Volume: 13, P: 1072-1081
A tumor-specific conditionally replicative adenovirus vector expressing TRAIL for gene therapy of hepatocellular carcinoma

X-W Ren
M Liang
F Hu
Research05 Aug 2005
Cancer Gene Therapy

Volume: 13, P: 159-168

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