Nature Search

Seismic Travel Time Evidence for Lateral Inhomogeneity in the Deep Mantle

BRUCE R. JULIAN
MRINAL K. SENGUPTA
Research13 Apr 1973
Nature

Volume: 242, P: 443-447
Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection

Understanding the mechanisms behind clinical immunity to malaria is crucial for developing effective interventions. Here, the authors demonstrate that clinical immunity to Plasmodium vivax develops rapidly after a single controlled human malaria infection, reducing inflammatory responses and protecting against symptoms, while not significantly affecting parasite load.

Mimi M. Hou
Adam C. Harding
Angela M. Minassian
ResearchOpen Access25 Sept 2025
Nature Communications

Volume: 16, P: 1-13
Mechanism of Kasugamycin Resistance in Escherichia coli

TERRY L. HELSER
JULIAN E. DAVIES
JAMES E. DAHLBERG
Research05 Jan 1972
Nature New Biology

Volume: 235, P: 6-9
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
PKJKP

BRUCE R. JULIAN
DAVID DAVIES
ROBERT M. SHEPPARD
Research11 Feb 1972
Nature

Volume: 235, P: 317-318
Change in Methylation of 16S Ribosomal RNA Associated with Mutation to Kasugamycin Resistance in Escherichia coli

TERRY L. HELSER
JULIAN E. DAVIES
JAMES E. DAHLBERG
Research01 Sept 1971
Nature New Biology

Volume: 233, P: 12-14
Evidence for enhancer activity in intron 1 of TNFRSF1A using CRISPR/Cas9 in human induced pluripotent stem cell-derived macrophages

Julie A. Osgood
Andrew C. Brown
Julian C. Knight
ResearchOpen Access07 Oct 2025
Scientific Reports

Volume: 15, P: 1-13
Antibiotic inhibition of group I ribozyme function

Uwe von Ahsen
Julian Davies
Renée Schroeder
Research26 Sept 1991
Nature

Volume: 353, P: 368-370
Biology of Adult Mosquitoes in Eastern Colombia

JULIAN de ZULUETA
Research29 Jul 1950
Nature

Volume: 166, P: 180-181
Expression of a transposable antibiotic resistance element in Saccharomyces

Antonio Jimenez
Julian Davies
Research30 Oct 1980
Nature

Volume: 287, P: 869-871
Genetic Analysis of an E. coli Strain with a Mutation affecting DNA Polymerase

JULIAN GROSS
MARILYN GROSS
Research20 Dec 1969
Nature

Volume: 224, P: 1166-1168
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau

The relationship between lipid dyshomeostasis and tau pathology in FTLD and AD remains unclear. Here, the authors demonstrate that GRAMD1B contributes to lipid dyshomeostasis, autophagy impairment, and tau hyperphosphorylation in neurons.

Diana Acosta Ingram
Emir Turkes
Hongjun Fu
ResearchOpen Access09 Apr 2025
Nature Communications

Volume: 16, P: 1-24
Trichodermin resistance—mutation affecting eukaryotic ribosomes

DANIEL SCHINDLER
PAUL GRANT
JULIAN DAVIES
Research05 Apr 1974
Nature

Volume: 248, P: 535-536
Phenotypic suppression and misreading in Saccharomyces cerevisiae

ARJUN SINGH
DORIS URSIC
JULIAN DAVIES
Research01 Jan 1979
Nature

Volume: 277, P: 146-148
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Stimulation of p21^ras upon T-cell activation

Julian Downward
Jonathan D. Graves
Doreen A. Cantrell
Research23 Aug 1990
Nature

Volume: 346, P: 719-723
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Relative value

Julian Davies
Comments & Opinion27 Sept 1984
Nature

Volume: 311, P: 317-318
Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes

This study uncovered genetic associations with environmental sensitivity in psychiatric and neurodevelopmental traits in an international collaboration using data from more than 21,000 monozygotic twins—the largest genetic study of monozygotic twin differences to date.

Elham Assary
Jonathan R. I. Coleman
Robert Keers
ResearchOpen Access10 Jun 2025
Nature Human Behaviour

Volume: 9, P: 1683-1696
Multiplication in specialization

Journal of Biotechnology. Managing editor A. Fiechter. Elsevier. 12/yr. Dfl. 861, $347. Biotechnology Progress: A Journal of Food, Pharmaceutical and Bioengineering. Editor M. L. Shuler. American Institute of Chemical Engineers. 4/yr. US $50; elsewhere $55. MIRCEN Journal of Applied Microbiology and Biotechnology: A Research Journal for Biotechnology in the Developing World. Editors J.C. Senez and F. A. Skinner. Oxford University Press. 4/yr. UK £20; North America $45; elsewhere £25.

Julian Davies
Comments & Opinion25 Sept 1986
Nature

Volume: 323, P: 368
Open resistance

Julian Davies
Books & Arts17 Sept 1987
Nature

Volume: 329, P: 212
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Cognitive function is associated with health and important life outcomes. Here, the authors perform a genome-wide association study for general cognitive function in 300,486 individuals and identify genetic loci that implicate neural and cell developmental pathways in this trait.

Gail Davies
Max Lam
Ian J. Deary
ResearchOpen Access29 May 2018
Nature Communications

Volume: 9, P: 1-16
Bacteria on the rampage

Julian Davies
News & Views19 Sept 1996
Nature

Volume: 383, P: 219-220
Bulls, bears and bugs

Julian Davies
Books & Arts02 Nov 1989
Nature

Volume: 342, P: 25-26
Enzymatic Inactivation of Streptomycin by R Factor-resistant Escherichia coli

TAKESHI YAMADA
DONALD TIPPER
JULIAN DAVIES
Research01 Jul 1968
Nature

Volume: 219, P: 288-291
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Creating expert patients: outcomes from a national digital therapeutic approach for people with asthma in Wales

Simon M. Barry
Julian Forton
Chris Davies
ResearchOpen Access09 Jun 2025
npj Primary Care Respiratory Medicine

Volume: 35, P: 1-6
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Redefined ion association constants have consequences for calcium phosphate nucleation and biomineralization

While clusters in calcium orthophosphate nucleation have long been known, their speciation and mechanistic pathways to hydroxyapatite remain debated. Here the authors report a revision of ion association in the calcium phosphate system and explore the consequences thereof on the early stages of phase separation.

David P. McDonogh
Julian D. Gale
Denis Gebauer
ResearchOpen Access18 Apr 2024
Nature Communications

Volume: 15, P: 1-13
Long-term thermo-mechanical properties of the continental lithosphere

Garry D. Karner
Michael S. Steckler
Julian A. Thorne
Research21 Jul 1983
Nature

Volume: 304, P: 250-253
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Analyses of 2,658 whole genomes across 38 types of cancer identify the contribution of non-coding point mutations and structural variants to driving cancer.

Esther Rheinbay
Morten Muhlig Nielsen
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature

Volume: 578, P: 102-111
Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell lines

Sarah J. Cumbers
Gareth T. Williams
Michael S. Neuberger
Research15 Oct 2002
Nature Biotechnology

Volume: 20, P: 1129-1134
A Chemically Specified Molecular Mechanism Underlying Excitation in Nerve: A Hypothesis

JULIAN M. TOBIAS
Research01 Jul 1964
Nature

Volume: 203, P: 13-17
Action of formamidine pesticides on octopamine receptors

Peter D. Evans
Julian D. Gee
Research04 Sept 1980
Nature

Volume: 287, P: 60-62
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

With the generation of large pan-cancer whole-exome and whole-genome sequencing projects, a question remains about how comparable these datasets are. Here, using The Cancer Genome Atlas samples analysed as part of the Pan-Cancer Analysis of Whole Genomes project, the authors explore the concordance of mutations called by whole exome sequencing and whole genome sequencing techniques.

Matthew H. Bailey
William U. Meyerson
Christian von Mering
ResearchOpen Access21 Sept 2020
Nature Communications

Volume: 11, P: 1-27
Many strands converge

Julian Blow
News & Views01 Apr 1987
Nature

Volume: 326, P: 441-442
Limb diversity, what can be more curious?

Julian Lewis
Books & Arts28 May 1981
Nature

Volume: 291, P: 363
Pan-cancer analysis of whole genomes

The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 cancer whole genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.

Lauri A. Aaltonen
Federico Abascal
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature

Volume: 578, P: 82-93
Formation of proinsulin by immobilized Bacillus subtilis

Klaus Mosbach
Staffan Birnbaum
Leif Bülow
Research01 Apr 1983
Nature

Volume: 302, P: 543-545
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

In this study, Aggarwal and colleagues perform prospective sequencing of SARS-CoV-2 isolates derived from asymptomatic student screening and symptomatic testing of students and staff at the University of Cambridge. They identify important factors that contributed to within university transmission and onward spread into the wider community.

Dinesh Aggarwal
Ben Warne
Ian G. Goodfellow
ResearchOpen Access08 Feb 2022
Nature Communications

Volume: 13, P: 1-16
Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele

Simon T. Bennett
Amanda J. Wilson
John A. Todd
Research01 Nov 1997
Nature Genetics

Volume: 17, P: 350-352
Trends in low global warming potential inhaler prescribing: A UK-wide cohort comparison from 2018–2024

Simon M. Barry
Gareth R. Davies
Chris R. Davies
ResearchOpen Access20 Feb 2025
npj Primary Care Respiratory Medicine

Volume: 35, P: 1-3
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
Ppd-1 is a key regulator of inflorescence architecture and paired spikelet development in wheat

By genetic studies the authors report a gene, Ppd-1, which controls paired spikelet development in wheat by regulating the expression of FT. Modulating the expression of Ppd-1 and FT can be used to improve grain-producing spikelets in wheat.

Scott A. Boden
Colin Cavanagh
Steve M. Swain
Research26 Jan 2015
Nature Plants

Volume: 1, P: 1-6
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Combined burden and functional impact tests for cancer driver discovery using DriverPower

Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding and non-coding driver mutations within cancer whole genomes via consideration of mutational burden and functional impact evidence.

Shimin Shuai
Federico Abascal
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Communications

Volume: 11, P: 1-12
Genomic footprints of activated telomere maintenance mechanisms in cancer

In somatic cells the mechanisms maintaining the chromosome ends are normally inactivated; however, cancer cells can re-activate these pathways to support continuous growth. Here, the authors characterize the telomeric landscapes across tumour types and identify genomic alterations associated with different telomere maintenance mechanisms.

Lina Sieverling
Chen Hong
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Communications

Volume: 11, P: 1-13
An imprinted gene(s) for diabetes?

I. Karen Temple
Rowena S. James
Julian P.H. Shield
Correspondence01 Feb 1995
Nature Genetics

Volume: 9, P: 110-112
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

In this study the authors consider the structural variants (SVs) present within cancer cases of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. They report hundreds of genes, including known cancer-associated genes for which the nearby presence of a SV breakpoint is associated with altered expression.

Yiqun Zhang
Fengju Chen
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Communications

Volume: 11, P: 1-14

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