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Showing 1–4 of 4 results
Advanced filters: Author: Jaanus Remme Clear advanced filters

  • The tethered ribosome system Ribo-T supports cell proliferation though at a reduced rate. Here the authors show this is due to slower ribosome assembly instead of reduced functionality.

    • Nikolay A. Aleksashin
    • Margus Leppik
    • Alexander S. Mankin
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13

  • Elongation factor P is a conserved translational regulatory protein that has an unusual post-translational modification, in which Lys34 forms an amide linkage to (R)-β-lysine. Further characterization reveals that Lys34 is also hydroxylated, drawing parallels to a functional modification of eukaryotic initiation factor 5A.

    • Lauri Peil
    • Agata L Starosta
    • Daniel N Wilson
    Research
    Nature Chemical Biology
    Volume: 8, P: 695-697

  • Ribosomes of all organisms have retained 5S rRNA as an autonomous rRNA species. Here the authors engineer a bacterial strain with ribosomes that do not have free 5S rRNA, and carry structural analyses that suggest the evolutionary preservation of 5S rRNA as an independent molecule is based on its role in the dynamic process of ribosome biogenesis.

    • Shijie Huang
    • Nikolay A. Aleksashin
    • Alexander S. Mankin
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13