Toll-like receptors (TLRs) have a central role in the initiation of innate and adaptive immune responses. Recent studies have shown that various accessory molecules are required for the biosynthesis and/or activation of several TLRs. A detailed knowledge of these accessory molecules is necessary to better understand the function of TLRs in the immune system.
- Clarissa C. Lee
- Ana M. Avalos
- Hidde L. Ploegh
