Nature Search

Distinct rat proteins can recognize CCAAT-homologous sequences of the metallothionein promoter and trans-activate this promoter

Lyudmila P Aniskovitch
Samson T Jacob
Research31 Mar 1998
Oncogene

Volume: 16, P: 1475-1486
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Large genome-wide meta-analysis of clinically diagnosed late-onset Alzheimer’s disease (LOAD) from 94,437 individuals identifies new LOAD risk loci and implicates Aβ formation, tau protein binding, immune response and lipid metabolism.

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Research28 Feb 2019
Nature Genetics

Volume: 51, P: 414-430
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Crystal structure of Epiphyas postvittana pheromone binding protein 3

Cyril Hamiaux
Colm Carraher
Jacob A. Corcoran
ResearchOpen Access01 Oct 2020
Scientific Reports

Volume: 10, P: 1-11
Knockdown of an ATP-binding cassette transporter in resistant western corn rootworm larvae partially reverses resistance to eCry3.1Ab protein

Adriano E. Pereira
Kyle J. Paddock
Man P. Huynh
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-13
Endogenous insensitivity to the Orco agonist VUAA1 reveals novel olfactory receptor complex properties in the specialist fly Mayetiola destructor

Jacob A. Corcoran
Yonathan Sonntag
Christer Löfstedt
ResearchOpen Access22 Feb 2018
Scientific Reports

Volume: 8, P: 1-13
The yin and yang of chromosomal instability in prostate cancer

Chromosomal instability is a hallmark of advanced prostate cancer. In this Review, the authors discuss the biological causes and paradoxical consequences of chromosomal instability, its potential clinical role in the stratification of prostate cancer aggressiveness and the development of novel treatment strategies.

Marc Carceles-Cordon
Jacob J. Orme
Veronica Rodriguez-Bravo
Reviews02 Feb 2024
Nature Reviews Urology

Volume: 21, P: 357-372
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Amendments and Corrections15 Aug 2019
Nature Genetics

Volume: 51, P: 1423-1424
Identification and functional characterization of the first molluscan neuromedin U receptor in the slug, Deroceras reticulatum

Seung-Joon Ahn
Rory J. Mc Donnell
Man-Yeon Choi
ResearchOpen Access18 Dec 2020
Scientific Reports

Volume: 10, P: 1-13
A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells

Maria Moeller
Nicole M Haynes
Phillip K Darcy
Research02 Apr 2004
Cancer Gene Therapy

Volume: 11, P: 371-379

Search

Distinct rat proteins can recognize CCAAT-homologous sequences of the metallothionein promoter and trans-activate this promoter

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Mapping the human genetic architecture of COVID-19

A second update on mapping the human genetic architecture of COVID-19

Whole-genome sequencing reveals host factors underlying critical COVID-19

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Crystal structure of Epiphyas postvittana pheromone binding protein 3

Knockdown of an ATP-binding cassette transporter in resistant western corn rootworm larvae partially reverses resistance to eCry3.1Ab protein

Endogenous insensitivity to the Orco agonist VUAA1 reveals novel olfactory receptor complex properties in the specialist fly Mayetiola destructor

The yin and yang of chromosomal instability in prostate cancer

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Identification and functional characterization of the first molluscan neuromedin U receptor in the slug, Deroceras reticulatum

A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells

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