The activation and infiltration of immune cells to the vasculature is intimately linked to the immunopathology of hypertension. Here the authors implicate PI3Kγ signalling in the trafficking of CD8+ T cells between lymphoid and non-lymphoid organs, and the development of hypertension in a murine model.
- Marialuisa Perrotta
- Sara Perrotta
- Daniela Carnevale