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Showing 1–4 of 4 results
Advanced filters: Author: Jaeeon Lee Clear advanced filters

  • The functional roles of the striatal indirect pathway remain unclear. In this Perspective, Lee and Sabatini propose that a three-factor learning rule governs the activity of indirect striatal projection neurons, contributing to the learnt avoidance of actions with negative outcomes and the transition to alternative actions.

    • Jaeeon Lee
    • Bernardo L. Sabatini
    Reviews
    Nature Reviews Neuroscience
    Volume: 26, P: 438-449

  • Fiber photometry with tapered fibers allows monitoring of neural activity in larger volumes than with flat-cleaved fibers. In addition, signals from different depths can be resolved with the same tapered fiber.

    • Filippo Pisano
    • Marco Pisanello
    • Ferruccio Pisanello
    Research
    Nature Methods
    Volume: 16, P: 1185-1192

  • This study demonstrates that basal ganglia functional topography is maintained across and downstream of its output nuclei, and in closed loops. Focal stimulation of distinct striatal subregions induces distinct action, supporting a model of parallel behavioral control.

    • Jaeeon Lee
    • Wengang Wang
    • Bernardo L. Sabatini
    Research
    Nature Neuroscience
    Volume: 23, P: 1388-1398