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Showing 1–2 of 2 results
Advanced filters: Author: James Chettle Clear advanced filters

  • Intraepithelial lymphocytes in the gut eliminate dysfunctional epithelial cells and promote regrowth of healthy cells. Here the authors show that, in addition, these lymphocytes protect cells against viral infections by rapidly activating interferon-dependent pathways in intestinal epithelial cells.

    • Mahima Swamy
    • Lucie Abeler-Dörner
    • Adrian C. Hayday
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-12

  • The tetronate ring appears in several natural products, but the biosynthetic path to this structure has proven elusive. Reconstitution of a polyketide assembly line and in vitro assays with a chemically synthesized intermediate now point to a single enzyme as catalyzing ring formation.

    • Yuhui Sun
    • Frank Hahn
    • Peter F Leadlay
    Research
    Nature Chemical Biology
    Volume: 6, P: 99-101