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  • Oxidized host-derived phospholipids such as oxPAPC can play important roles in atherosclerosis. Zanoni and colleagues demonstrate that oxPAPC generates a distinctive metabolic and hyperinflammatory profile in macrophages that can drive atherosclerosis in mice.

    • Marco Di Gioia
    • Roberto Spreafico
    • Ivan Zanoni
    Research
    Nature Immunology
    Volume: 21, P: 42-53